Reactome | GUCA1B [cytosol]

GUCA1B [cytosol]

Stable Identifier

R-HSA-55479

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Guanylyl cyclase activating protein 2, GCAP 2, Guanylate cyclase activator 1B

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by GPCR (Homo sapiens)
  - GPCR downstream signalling (Homo sapiens)
    - G alpha (i) signalling events (Homo sapiens)
      - Visual phototransduction (Homo sapiens)
        
        The phototransduction cascade (Homo sapiens)
        
        Inactivation, recovery and regulation of the phototransduction cascade (Homo sapiens)
        
        GUCYs converts GTP to cGMP (Homo sapiens)
        
        GCAP2:Ca2+ [cytosol] (Homo sapiens)
        
        GUCA1B [cytosol] (Homo sapiens)
        
        GUCA1B [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9UMX6 GUCA1B

Gene Names

GUCA1B, GCAP2

Chain

initiator methionine:1, chain:2-200

Reference Genes

BioGPS Gene:2979 GUCA1B

COSMIC (genes):GUCA1B GUCA1B

CTD Gene:2979 GUCA1B

dbSNP Gene:2979 GUCA1B

ENSEMBL:ENSG00000112599 GUCA1B

HGNC:4679 GUCA1B

KEGG Gene (Homo sapiens):2979 GUCA1B

Monarch:2979 GUCA1B

NCBI Gene:2979 GUCA1B

OMIM:602275 GUCA1B

UCSC:Q9UMX6 GUCA1B

Reference Transcript

RefSeq:NM_002098.5 GUCA1B

Other Identifiers

0000130114

11725810_at

17019199

215841_at

235528_at

2953975

2953976

2953979

2953980

2953981

2953988

2953989

2979

40557_at

52723_at

8126387

A_23_P81825

A_32_P64200

GE81116

GO:0001750

GO:0001917

GO:0003674

GO:0005509

GO:0005515

GO:0005575

GO:0005886

GO:0005929

GO:0006810

GO:0007165

GO:0007168

GO:0007267

GO:0007589

GO:0007601

GO:0007602

GO:0008048

GO:0008150

GO:0009058

GO:0016020

GO:0022400

GO:0030234

GO:0030249

GO:0031282

GO:0031284

GO:0034641

GO:0042995

GO:0043167

GO:0043226

GO:0044281

GO:0046872

GO:0050877

GO:0050896

GO:0097381

GO:0120199

Hs.284258.0.S1_3p_at

Hs.32804.0.A1_3p_at

ILMN_1689264

ILMN_2211728

PH_hs_0026103

TC06001730.hg

Participant Of

hasComponent

GCAP2:Ca2+ [cytosol]

This entity regulates

Positively

GUCYs converts GTP to cGMP

Other forms of this molecule

GUCA1B [photoreceptor disc membrane]

Inferred To

Dmel\CG7646 [cytosol] (Drosophila melanogaster)

cbpK [cytosol] (Dictyostelium discoideum)

cbpL [cytosol] (Dictyostelium discoideum)

GUCA1B [cytosol] (Canis familiaris)

GUCA1B [cytosol] (Dictyostelium discoideum)

GUCA1B [cytosol] (Gallus gallus)

GUCA1B [cytosol] (Sus scrofa)

Nca [cytosol] (Drosophila melanogaster)

Guca1b [cytosol] (Mus musculus)

Guca1b [cytosol] (Rattus norvegicus)

guca1b [cytosol] (Danio rerio)

cbpM [cytosol] (Dictyostelium discoideum)

phyh [cytosol] (Xenopus tropicalis)

Homologues of GUCA1B [cytosol] (Dictyostelium discoideum)

Homologues of GUCA1B [cytosol] (Drosophila melanogaster)

cbpJ [cytosol] (Dictyostelium discoideum)

ncsA [cytosol] (Dictyostelium discoideum)

Cross References

RefSeq

NP_002089.4

OpenTargets

ENSG00000112599

GeneCards

Q9UMX6

HPA

ENSG00000112599-GUCA1B

Ensembl

ENST00000230361, ENSG00000112599, ENSP00000230361

PRO

Q9UMX6

Orphanet

18431

HMDB Protein

HMDBP07723

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P32243-2 OTX2			0.556	3