Reactome | GUCA1B [cytosol]

GUCA1B

Stable Identifier

R-HSA-55479

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Guanylyl cyclase activating protein 2, GCAP 2, Guanylate cyclase activator 1B

Locations in the PathwayBrowser

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Signal Transduction (Homo sapiens)

- Signaling by GPCR (Homo sapiens)
  - GPCR downstream signalling (Homo sapiens)
    - G alpha (i) signalling events (Homo sapiens)
      - Visual phototransduction (Homo sapiens)
        
        The phototransduction cascade (Homo sapiens)
        
        Inactivation, recovery and regulation of the phototransduction cascade (Homo sapiens)
        
        GUCYs converts GTP to cGMP (Homo sapiens)
        
        GCAP2:Ca2+ [cytosol] (Homo sapiens)
        
        GUCA1B [cytosol] (Homo sapiens)
        
        GUCA1B [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9UMX6 GUCA1B

Gene Names

GUCA1B, GCAP2

Chain

initiator methionine:1, chain:2-200

Reference Genes

BioGPS Gene:2979 GUCA1B

COSMIC (genes):GUCA1B GUCA1B

CTD Gene:2979 GUCA1B

dbSNP Gene:2979 GUCA1B

ENSEMBL:ENSG00000112599 GUCA1B

HGNC:4679 GUCA1B

KEGG Gene (Homo sapiens):hsa:2979 GUCA1B

Monarch:2979 GUCA1B

NCBI Gene:2979 GUCA1B

OMIM:602275 GUCA1B

UCSC:Q9UMX6 GUCA1B

Reference Transcript

RefSeq:NM_002098.5 GUCA1B

Other Identifiers

0000130114

17019199

215841_at

2953976

2953979

2953980

2953981

2953988

2953989

2979

40557_at

55479

8126387

A_23_P81825

AAD47279

AF173227

AF173228

AF173229

AL096814

CCDS4865

ENSG00000112599

ENSP00000230361

ENST00000230361

EntrezGene:2979

GE81116

GO:0001750

GO:0001917

GO:0003674

GO:0005509

GO:0005575

GO:0005623

GO:0005886

GO:0005929

GO:0006810

GO:0007165

GO:0007168

GO:0007267

GO:0007589

GO:0007601

GO:0007602

GO:0008048

GO:0008150

GO:0009058

GO:0016020

GO:0022400

GO:0030234

GO:0030249

GO:0031282

GO:0031284

GO:0034641

GO:0043167

GO:0043226

GO:0044281

GO:0046872

GO:0050877

GO:0050896

GO:0097381

GUCA1B

GUCA1B-201

HGNC:4679

HPA031453

Hs.284258.0.S1_3p_at

IPR002048

IPR011992

IPR015756

IPR018247

MIM:602275

MIM:613827

NM_002098

NP_002089

PF13202

PF13499

PH_hs_0026103

PR00450

SM00054

TC06001730.hg

uc003orz.4

UPI000013C92C

Participant Of

hasComponent

GCAP2:Ca2+ [cytosol]

This entity regulates

Positive Regulation

Positive regulation by 'GUCA1B [cytosol]'

Other forms of this molecule

GUCA1B [photoreceptor disc membrane]

Inferred To

GUCA1B [cytosol] (Bos taurus)

GUCA1B [cytosol] (Canis familiaris)

GUCA1B [cytosol] (Danio rerio)

GUCA1B [cytosol] (Dictyostelium discoideum)

GUCA1B [cytosol] (Drosophila melanogaster)

GUCA1B [cytosol] (Mus musculus)

GUCA1B [cytosol] (Rattus norvegicus)

GUCA1B [cytosol] (Sus scrofa)

GUCA1B [cytosol] (Xenopus tropicalis)

Homologues of GUCA1B [cytosol] (Bos taurus)

Homologues of GUCA1B [cytosol] (Drosophila melanogaster)

Homologues of GUCA1B [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_002089.4

GeneCards

Q9UMX6

PRO

Q9UMX6

Orphanet

18431

HMDB Protein

HMDBP07723

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P32243-2 OTX2			0.488	2