1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2]

Stable Identifier
Reaction [transition]
Homo sapiens
Conversion of Diacylglycerol to Triacylglycerol [DGAT2]
Locations in the PathwayBrowser
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Diacylglycerol O-acyltransferase 1 (DGAT2) associated with the endoplasmic reticulum membrane catalyzes the reaction of 1,2-diacyl-glycerol and acyl-CoA to form triacylglycerol + CoASH (Cases et al. 2001, Wakimoto et al. 2003).

Literature References
PubMed ID Title Journal Year
11481335 Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members

Tow, B, Stone, SJ, Voelker, T, Cases, S, Lardizabal, KD, Yen, E, Farese, RV, Zhou, P

J Biol Chem 2001
14521909 A novel diacylglycerol acyltransferase (DGAT2) is decreased in human psoriatic skin and increased in diabetic mice

Okubo, K, Mitsui, H, Imai, Y, Seishima, M, Wakimoto, K, Kawasaki, S, Chiba, H, Torii, H, Michibata, H

Biochem Biophys Res Commun 2003
Catalyst Activity

diacylglycerol O-acyltransferase activity of DGAT2 [endoplasmic reticulum membrane]

Orthologous Events
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