G3P is acylated to 1-acyl LPA by AGPAT6

Stable Identifier
R-HSA-549112
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [ER membrane-associated], Conversion of glycerol-3-phosphate to lysophosphatidic acid
Locations in the PathwayBrowser
Summation

Glycerol-3-phosphate (G3P) is acylated to 1-acyl lysophosphatidic acid (LPA) by the enzymes glycerol-3-phosphate acyltransferase 4 (AGPAT6) at the endoplasmic reticulum (ER) membrane (Cao et al., 2006; Chen et al., 2008).

Participants
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
glycerol-3-phosphate O-acyltransferase activity of AGPAT6 [endoplasmic reticulum membrane]
Physical Entity
Activity
Orthologous Events