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NRP2 [plasma membrane]
Stable Identifier
R-HSA-549042
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Neuropilin-2, NRP2_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
L1CAM interactions (Homo sapiens)
NrCAM interactions (Homo sapiens)
NrCAM binds Neuropilin-2 (Homo sapiens)
NRP2 [plasma membrane] (Homo sapiens)
NRP2:NrCAM [plasma membrane] (Homo sapiens)
NRP2 [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by VEGF (Homo sapiens)
Neurophilin interactions with VEGF and VEGFR (Homo sapiens)
NRP-2 associates with VEGFR1 forming complexes on cell surface (Homo sapiens)
NRP2 [plasma membrane] (Homo sapiens)
NRP2:VEGFR1 dimer [plasma membrane] (Homo sapiens)
NRP2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60462 NRP2
Gene Names
NRP2, VEGF165R2
Chain
signal peptide:1-20, chain:21-931
Reference Genes
BioGPS Gene:8828 NRP2
COSMIC (genes):NRP2 NRP2
CTD Gene:8828 NRP2
dbSNP Gene:8828 NRP2
ENSEMBL:ENSG00000118257 NRP2
HGNC:8005 NRP2
KEGG:hsa:8828 NRP2
Monarch:8828 NRP2
NCBI Gene:8828 NRP2
OMIM:602070 NRP2
UCSC:O60462 NRP2
Reference Transcript
RefSeq:NM_201266.2 NRP2
RefSeq:XM_047446172.1 NRP2
RefSeq:XM_005246933.3 NRP2
RefSeq:XM_047446174.1 NRP2
RefSeq:XM_005246934.3 NRP2
RefSeq:NM_018534.3 NRP2
RefSeq:XM_054344364.1 NRP2
RefSeq:XM_054344363.1 NRP2
RefSeq:XM_054344368.1 NRP2
RefSeq:XM_054344366.1 NRP2
RefSeq:NM_201264.2 NRP2
RefSeq:NM_003872.2 NRP2
RefSeq:XM_054344367.1 NRP2
RefSeq:XM_047446171.1 NRP2
RefSeq:XM_047446170.1 NRP2
RefSeq:XM_017005185.1 NRP2
RefSeq:XM_017005186.1 NRP2
RefSeq:XM_047446173.1 NRP2
RefSeq:XM_047446175.1 NRP2
RefSeq:XM_054344369.1 NRP2
RefSeq:NM_201279.2 NRP2
RefSeq:XM_054344365.1 NRP2
RefSeq:XM_047446176.1 NRP2
RefSeq:NM_201267.2 NRP2
Other Identifiers
11716967_a_at
11716968_a_at
11716969_a_at
11716970_a_at
11733332_at
11733333_s_at
11733334_a_at
11733665_a_at
11762100_at
1555468_3p_at
1555468_PM_at
1555468_at
16889879
210841_PM_s_at
210841_s_at
210842_PM_at
210842_at
211844_PM_s_at
211844_s_at
214632_PM_at
214632_at
219367_PM_s_at
219367_s_at
222877_PM_at
222877_at
223510_PM_at
223510_at
225566_PM_at
225566_at
229225_PM_at
229225_at
2524312
2524313
2524314
2524315
2524316
2524317
2524318
2524319
2524320
2524325
2524335
2524336
2524337
2524338
2524339
2524343
2524344
2524356
2524357
2524358
2524359
2524374
2524375
2524377
2524378
2524380
2524382
2524391
2524392
2524393
2524394
2524395
2524396
2524397
2524399
2524400
2524402
2524403
2524414
2524415
2524416
2524417
2524418
2524420
2524421
2524422
2524429
2524430
2524431
2524432
2524441
2524442
2524443
2524444
2524445
2524446
2524447
2524448
2524449
2524450
33853_s_at
41304_at
43463_at
53983_at
58873_at
65729_at
67678_r_at
8047738
8047763
86231_r_at
8828
88661_f_at
A_14_P112603
A_23_P209669
A_23_P393727
A_23_P429555
A_24_P50801
A_24_P84130
A_33_P3297415
GE54130
GE82398
GE832823
GE84611
GE87403
GO:0001525
GO:0001764
GO:0001938
GO:0002116
GO:0003148
GO:0003824
GO:0005021
GO:0005515
GO:0005576
GO:0005886
GO:0007155
GO:0007399
GO:0007411
GO:0007507
GO:0008201
GO:0010595
GO:0016020
GO:0016740
GO:0017154
GO:0019838
GO:0019955
GO:0021612
GO:0021637
GO:0021649
GO:0021675
GO:0021785
GO:0021828
GO:0030154
GO:0030424
GO:0036484
GO:0036486
GO:0038023
GO:0038084
GO:0042802
GO:0045211
GO:0046872
GO:0048846
GO:0048856
GO:0048870
GO:0050919
GO:0060089
GO:0061549
GO:0061551
GO:0071526
GO:0097374
GO:0097490
GO:0097491
GO:0098978
GO:0099175
GO:0140096
GO:1901166
GO:1903375
GO:1904835
GO:1990830
HMNXSV003027986
HMNXSV003036850
Hs.17778.2.A1_3p_at
Hs.17778.6.A1_3p_at
Hs.17778.8.S2_3p_at
Hs.63382.0.S2_3p_at
Hs2.17778.5.S1_3p_x_at
ILMN_1787190
ILMN_1910180
ILMN_2274306
ILMN_2376484
PH_hs_0024081
PH_hs_0032897
TC02001206.hg
g11907927_3p_at
g11907929_3p_a_at
g2547129_3p_a_at
g8924189_3p_s_at
Participates
as a component of
NRP2:NrCAM [plasma membrane] (Homo sapiens)
NRP2:VEGFR1 dimer [plasma membrane] (Homo sapiens)
as an input of
NrCAM binds Neuropilin-2 (Homo sapiens)
NRP-2 associates with VEGFR1 forming complexes on cell surface (Homo sapiens)
Inferred To
NRP2 [plasma membrane]
(Bos taurus)
NRP2 [plasma membrane]
(Canis familiaris)
NRP2 [plasma membrane]
(Gallus gallus)
NRP2 [plasma membrane]
(Sus scrofa)
Nrp2 [plasma membrane]
(Mus musculus)
Nrp2 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_957716.1
,
NP_957719.1
,
NP_957718.1
,
XP_047302131.1
,
XP_047302130.1
,
XP_047302132.1
,
NP_003863.2
,
XP_054200343.1
,
XP_054200342.1
,
XP_047302127.1
,
XP_047302126.1
,
XP_005246990.2
,
XP_005246991.2
,
XP_047302129.1
,
XP_047302128.1
,
XP_054200341.1
,
XP_054200340.1
,
XP_054200344.1
,
XP_016860675.1
,
XP_054200339.1
,
XP_054200338.1
,
NP_958436.1
,
XP_016860674.1
,
NP_061004.3
OpenTargets
ENSG00000118257
ENSEMBL
ENST00000357118
,
ENSP00000353582
,
ENST00000272849
,
ENST00000360409
,
ENST00000412873
,
ENSP00000387519
,
ENST00000357785
,
ENSP00000349632
,
ENSP00000407626
,
ENSP00000272849
,
ENST00000417189
,
ENSG00000118257
,
ENSP00000350432
HPA
ENSG00000118257-NRP2
GeneCards
NRP2
PRO
O60462
Pharos - Targets
O60462
GlyGen
O60462
PDB
2QQO
,
6TDB
,
7T4S
,
2QQJ
,
5DQ0
,
8IVX
,
8IVW
,
4QDR
,
7M22
,
2QQL
,
4QDS
,
2QQK
,
5DN2
,
4QDQ
,
6TJT
,
6GH8
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P97953-1 VEGFC
0.558
3
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