FADD

Stable Identifier
R-HSA-54639
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity), FADD protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
7538907 FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

Chinnaiyan, AM, O'Rourke, K, Tewari, M, Dixit, VM

Cell 1995
External Reference Information
External Reference
Gene Names
FADD, MORT1, GIG3
Chain
chain:1-208
Reference Transcript
Other Identifiers
0006350164
10209
11716799_at
11716800_at
1464
16728331
1A1W
1A1Z
1E3Y
1E41
202535_at
2GF5
3338425
3338426
3338427
3338428
3338431
3338432
3338433
3338434
3338435
38755_at
3EZQ
3OQ9
7942168
8772
A_14_P110132
A_14_P123448
A_23_P86917
A_24_P278637
AAA86517
AAH00334
AAP35573
AAS00484
ABD96828
AK291005
AY423721
BAF83694
BC000334
BT006927
CAA59197
CAB010209
CAG33019
CCDS8196
CH471076
CR456738
DQ449938
EAW74761
ENSG00000168040
ENSP00000301838
ENST00000301838
EntrezGene:8772
FADD
FADD-201
g4505228_3p_at
GE60092
GO:0001916
GO:0002020
GO:0002376
GO:0002821
GO:0003674
GO:0005123
GO:0005164
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006461
GO:0006915
GO:0006919
GO:0006950
GO:0007155
GO:0007165
GO:0007166
GO:0008150
GO:0008219
GO:0008283
GO:0008625
GO:0009058
GO:0016032
GO:0019899
GO:0022607
GO:0030154
GO:0031264
GO:0031265
GO:0032729
GO:0032757
GO:0032760
GO:0032813
GO:0033077
GO:0033612
GO:0034138
GO:0034641
GO:0035666
GO:0035877
GO:0036462
GO:0040011
GO:0042104
GO:0042220
GO:0042592
GO:0042802
GO:0042981
GO:0043005
GO:0043029
GO:0043065
GO:0043123
GO:0043226
GO:0043234
GO:0043278
GO:0044297
GO:0044403
GO:0045087
GO:0045121
GO:0045651
GO:0045862
GO:0045944
GO:0048148
GO:0048535
GO:0048536
GO:0048538
GO:0048856
GO:0048870
GO:0051604
GO:0051607
GO:0060340
GO:0060544
GO:0060546
GO:0065003
GO:0070236
GO:0071260
GO:0071550
GO:0089720
GO:0097049
GO:0097190
GO:0097191
GO:0097192
GO:0097202
GO:0097296
GO:0097342
GO:0097527
GO:1902041
GO:1902042
GO:1902043
GO:2000454
GO:2001238
HGNC:3573
HPA001464
ILMN_1758658
IPR000488
IPR001875
IPR011029
IPR016729
LRG_228
LRG_228t1
MIM:602457
MIM:613759
NM_003824
NP_003815
PF00531
PF01335
PH_hs_0004852
SM00005
SM00031
TC11000723.hg
U24231
uc001opm.3
UPI000012A4D1
X84709
X84709_at
Participant Of
Inferred To
Cross References
RefSeq
GeneCards
DOCK Blaster
PRO
Orphanet
Interactors (29)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q14790 CASP8  8 0.978 43
 UniProt:P25445 FAS  1 0.959 22
 UniProt:P50591 TNFSF10  1 0.913 19
 UniProt:P25445-1 FAS      0.883 17
 UniProt:Q13546 RIPK1  9 0.809 9
 UniProt:P25446  1 0.772 8
 UniProt:P48023 FASLG  1 0.758 4
 UniProt:Q92851 CASP10  4 0.75 4
 UniProt:Q15628 TRADD  1 0.721 4
 UniProt:Q13158 FADD  1 0.712 5
 UniProt:P53350 PLK1  4 0.676 9
 UniProt:Q99497 PARK7  2 0.653 9
 UniProt:B7UI21 B7UI21      0.593 7
 UniProt:P03126 VE6      0.593 4
 UniProt:O95243 MBD4  1 0.581 6
 UniProt:Q99836 MYD88  9 0.573 3
 UniProt:Q14790-5 CASP8      0.567 4
 UniProt:O00220 TNFRSF10A  1 0.527 3
 IntAct:EBI-16074260 EHECNLEB1      0.508 2
 UniProt:Q5S007 LRRK2  1 0.499 4
 UniProt:Q15560 TCEA2      0.488 2
 UniProt:P62324 BTG1      0.488 2
 UniProt:Q96D03 DDT4L      0.488 2
 UniProt:Q6PEW1 ZCH12      0.488 2
 UniProt:O00560 SDCBP  3 0.488 4
 UniProt:G2XKQ0 G2XKQ0      0.488 2
 UniProt:P78317 RNF4  2 0.488 2
 UniProt:B7ZLH0 B7ZLH0      0.488 2
 UniProt:Q14790-1 CASP8      0.482 5