Both MTRF1L and ICT1 can bind a standard stop codon in the A-site of the ribosome and cause release of the polypeptide. ICT1 can also cause release of ribosomes stalled in non-standard conformations (e.g. non-standard stop codons, mRNA lacking a stop codon) (inferred from pig mitoribosomes in Akabane et al. 2014).
Lind, C, Sund, J, Aqvist, J
Young, DJ, Edgar, CD, Murphy, J, Fredebohm, J, Poole, ES, Tate, WP
Akabane, S, Ueda, T, Nierhaus, KH, Takeuchi, N
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