Reactome | ELL [nucleoplasm]

ELL [nucleoplasm]

Stable Identifier

R-HSA-54257

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

RNA polymerase II elongation factor ELL, Eleven-nineteen lysine-rich leukemia protein

Locations in the PathwayBrowser for interactor UniProt:P0C1Z6

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External Reference Information

External Reference

UniProt:P55199 ELL

Gene Names

ELL, C19orf17

Chain

initiator methionine:, chain:2-621

Reference Genes

BioGPS Gene:8178 ELL

COSMIC (genes):ELL ELL

CTD Gene:8178 ELL

dbSNP Gene:8178 ELL

ENSEMBL:ENSG00000105656 ELL

ENSEMBL_homo_sapiens_GENE:ENSG00000105656.13 ELL

HGNC:23114 ELL

KEGG Gene (Homo sapiens):8178 ELL

Monarch:8178 ELL

NCBI Gene:8178 ELL

OMIM:600284 ELL

UCSC:P55199 ELL

Reference Transcript

RefSeq:NM_006532.3 ELL

Other Identifiers

11728333_a_at

11728334_a_at

11728335_a_at

1565254_PM_s_at

1565254_s_at

16870417

204095_PM_s_at

204095_s_at

204096_PM_s_at

204096_s_at

3855012

3855013

3855014

3855015

3855016

3855017

3855018

3855020

3855022

3855024

3855033

3855034

3855035

3855037

3855040

3855042

3855043

3855048

3855067

3855068

40044_at

62568_at

8035477

8178

A_23_P16537

A_23_P16538

A_23_P27936

A_33_P3406505

GE79578

GE83341

GO:0000791

GO:0000987

GO:0001701

GO:0003677

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005829

GO:0006351

GO:0006355

GO:0006366

GO:0006368

GO:0008023

GO:0015030

GO:0016073

GO:0016604

GO:0016607

GO:0019902

GO:0032786

GO:0032968

GO:0035363

GO:0042795

GO:0042796

GO:0043226

GO:0045945

GO:0048856

HMNXSV003013072

Hs.5881.0.S1_3p_a_at

Hs2.406233.6.S1_3p_s_at

ILMN_1736048

PH_hs_0000595

PH_hs_0029774

TC19001290.hg

U16282_at

g12053058_3p_a_at

Participates

as an output of

Elongating transcript encounters a lesion in the template (Homo sapiens)

as a member of

ELL,ELL2,ELL3 [nucleoplasm] (Homo sapiens)

as a component of

as an input of

This entity regulates

Positively

Recovery of RNA synthesis after TC-NER (Homo sapiens)

Inferred To

Ell [nucleoplasm] (Drosophila melanogaster)

Ell [nucleoplasm] (Mus musculus)

Ell [nucleoplasm] (Rattus norvegicus)

Ghost homologue of ELL [nucleoplasm] (Dictyostelium discoideum)

Ghost homologue of ELL [nucleoplasm] (Saccharomyces cerevisiae)

Ghost homologue of ELL [nucleoplasm] (Schizosaccharomyces pombe)

ELL [nucleoplasm] (Bos taurus)

ELL [nucleoplasm] (Gallus gallus)

ELL [nucleoplasm] (Sus scrofa)

ISYNA1 [nucleoplasm] (Canis familiaris)

wu:fc60b11 [nucleoplasm] (Danio rerio)

ell-1 [nucleoplasm] (Caenorhabditis elegans)

ell [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_006523.1

OpenTargets

ENSG00000105656

HPA

ENSG00000105656-ELL

GeneCards

P55199

Ensembl

ENSG00000105656, ENST00000262809, ENSP00000262809

PRO

P55199

Pharos - Targets

P55199

PDB

2DOA

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q659A1 ICE2	1	ICE2 [nucleoplasm] (R-HSA-6807421)	0.623	5
UniProt:Q9Y2F5 ICE1	1	ICE1 [nucleoplasm] (R-HSA-6807433)	0.623	4
UniProt:Q96H20 SNF8	1	SNF8 [cytosol] (R-HSA-917711)	0.602	3
UniProt:P62136 PPP1CA	1	PPP1CA [cytosol] (R-HSA-163525)	0.544	2
UniProt:Q96JC9 EAF1	1	EAF1 [nucleoplasm] (R-HSA-8932787)	0.527	2
UniProt:Q9UHB7 AFF4	1	AFF4 [nucleoplasm] (R-HSA-8932788)	0.527	2
UniProt:P0C1Z6 TFPT	1	TFPT [nucleoplasm] (R-HSA-5689542)	0.488	2

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