GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA

Stable Identifier
R-HSA-5419277
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
mitochondrial matrix, mitochondrial inner membrane
ReviewStatus
5/5
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GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
GFM2:GTP (EF-G2mt:GTP) joins MRRF at the A site of the ribosome after translation has been terminated by MTRF1L (MTRF1a) at a stop codon.
Literature References
PubMed ID Title Journal Year
19716793 EF-G2mt is an exclusive recycling factor in mammalian mitochondrial protein synthesis

Tsuboi, M, Morita, H, Nozaki, Y, Akama, K, Ueda, T, Ito, K, Nierhaus, KH, Takeuchi, N

Mol. Cell 2009
Participants
Input
Output
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as an event of
Authored
May, B  (2014-04-30)
Reviewed
Chrzanowska-Lightowlers, ZM  (2014-08-29)
Spremulli, LL  (2014-09-20)
Matthews, L  (2025-03-04)
Created
May, B  (2014-05-03)
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