Reactome | GFM1 [mitochondrial matrix]

GFM1 [mitochondrial matrix]

Stable Identifier

R-HSA-5389859

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

Elongation factor G, mitochondrial, EFGM_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96RP9 GFM1

Gene Names

GFM1, EFG, EFG1, GFM

Chain

transit peptide:1-36, chain:37-751

Reference Genes

BioGPS Gene:85476 GFM1

COSMIC (genes):GFM1 GFM1

CTD Gene:85476 GFM1

dbSNP Gene:85476 GFM1

ENSEMBL:ENSG00000168827 GFM1

HGNC:13780 GFM1

KEGG:hsa:85476 GFM1

Monarch:85476 GFM1

NCBI Gene:85476 GFM1

OMIM:606639 GFM1

UCSC:Q96RP9 GFM1

Reference Transcript

Other Identifiers

11719665_a_at

11754800_s_at

16947418

220903_PM_at

220903_at

225153_PM_at

225153_at

225158_PM_at

225158_at

225161_PM_at

225161_at

232295_PM_at

232295_at

232296_PM_s_at

232296_s_at

239900_3p_x_at

239900_PM_x_at

239900_x_at

2649642

2649643

2649644

2649646

2649647

2649648

2649649

2649650

2649651

2649652

2649653

2649654

2649657

2649659

2649660

2649661

2649662

2649664

2649665

2649667

2649668

2649669

2649676

2649677

2649678

2649679

2649680

2649681

2649682

2649685

2649686

2649687

2649688

2649689

2649690

2649691

2649692

2649693

2649694

2649695

2649697

2649699

2649701

2649703

52012_at

62332_r_at

67343_at

80567_at

8083630

85476

A_14_P104912

A_14_P133326

A_23_P155288

A_24_P76489

A_33_P3262133

GE62388

GE770898

GO:0000166

GO:0003723

GO:0003746

GO:0003824

GO:0003924

GO:0005515

GO:0005525

GO:0005737

GO:0005739

GO:0005759

GO:0006412

GO:0006414

GO:0016787

GO:0043226

GO:0045182

GO:0070125

HMNXSV003022517

HMNXSV003049898

Hs.270696.0.A1_3p_at

Hs.270696.0.A1_3p_x_at

Hs.274543.0.S1_3p_at

Hs.41066.0.A1_3p_at

Hs.41066.0.A2_3p_at

Hs.41066.0.A3_3p_at

ILMN_1657682

ILMN_1861523

PH_hs_0014174

TC03000866.hg

g13376503_3p_s_at

Participates

as a component of

Inferred To

GFM1 [mitochondrial matrix] (Bos taurus)

GFM1 [mitochondrial matrix] (Caenorhabditis elegans)

GFM1 [mitochondrial matrix] (Canis familiaris)

GFM1 [mitochondrial matrix] (Danio rerio)

GFM1 [mitochondrial matrix] (Drosophila melanogaster)

GFM1 [mitochondrial matrix] (Gallus gallus)

GFM1 [mitochondrial matrix] (Mus musculus)

GFM1 [mitochondrial matrix] (Rattus norvegicus)

GFM1 [mitochondrial matrix] (Sus scrofa)

Cross References

ENSEMBL

ENST00000486715, ENSG00000168827, ENSP00000264263, ENST00000264263, ENSP00000419038

OpenTargets

ENSG00000168827

GeneCards

GFM1

HPA

ENSG00000168827-GFM1

PRO

Q96RP9

Pharos - Targets

Q96RP9

GlyGen

Q96RP9

Orphanet

GFM1

HMDB Protein

HMDBP08369

PDB

6VLZ, 6YDP, 7A5K, 6YDW, 6VMI

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q969Q1 TRIM63	1	TRIM63 [cytosol] (R-HSA-976020)	0.508	2
UniProt:P03508 NS	5	NEP/NS2 [extracellular region] (R-FLU-169705) NEP/NS2 [endocytic vesicle membrane] (R-FLU-189148) NEP/NS2 [endosome lumen] (R-FLU-189176) NEP/NS2 [cytosol] (R-FLU-192845) NEP/NS2 [nucleoplasm] (R-FLU-169474)	0.499	2
UniProt:P10809 HSPD1	6	HSPD1(1-26) [mitochondrial matrix] (R-HSA-8986171) HSPD1(1-573) [mitochondrial inner membrane] (R-HSA-1299442) HSPD1 [mitochondrial inner membrane] (R-HSA-1299455) HSPD1(1-573) [mitochondrial intermembrane space] (R-HSA-1267963) HSPD1(1-573) [cytosol] (R-HSA-1267989) HSPD1 [mitochondrial matrix] (R-HSA-1299448)	0.483	3