TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome

Stable Identifier
R-HSA-5389842
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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As inferred from bovine homologs, interaction of the cognate aminoacyl-tRNA in the A-site with the codon in the mRNA causes TUFM (EF-Tu) to hydrolyze GTP. TUFM:GDP then dissociates from the ribosome.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
GTPase activity of 55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA:TUFM:GTP [mitochondrial inner membrane]
Physical Entity
Activity
Inferred From
Authored
Reviewed
Created
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