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Go!
ub-SHH variants [cytosol]
Stable Identifier
R-HSA-5387369
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Hh mutants abrogate ligand secretion (Homo sapiens)
Hh mutants are degraded by ERAD (Homo sapiens)
Hh processing variants are translocated to the cytosol in a VCP-dependent manner (Homo sapiens)
ub-SHH variants [cytosol] (Homo sapiens)
processing defective Hh variants are degraded by the proteasome (Homo sapiens)
ub-SHH variants [cytosol] (Homo sapiens)
Participants
members
ub SHH(24-462) C198S [cytosol]
(Homo sapiens)
candidates
ub SRR SHH variants [cytosol]
(Homo sapiens)
ub cholesterol site variants of SHH [cytosol]
(Homo sapiens)
ub SHH(24-462) W117G [cytosol]
(Homo sapiens)
ub SHH(24-462) W117R [cytosol]
(Homo sapiens)
Participates
as an output of
Hh processing variants are translocated to the cytosol in a VCP-dependent manner (Homo sapiens)
as an input of
processing defective Hh variants are degraded by the proteasome (Homo sapiens)
Disease
Name
Identifier
Synonyms
holoprosencephaly
DOID:4621
Holoprosencephaly sequence (disorder)
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