POLB [nucleoplasm]

Stable Identifier
R-HSA-53845
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
DNA polymerase beta (EC 2.7.7.7)
Icon
POLB [nucleoplasm] icon
POLB [nucleoplasm] icon
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:P06746 POLB
Gene Names
POLB
Chain
chain:1-335
Reference Genes
BioGPS Gene:5423 POLB
COSMIC (genes):POLB POLB
CTD Gene:5423 POLB
dbSNP Gene:5423 POLB
ENSEMBL:ENSG00000070501 POLB
HGNC:9174 POLB
Monarch:5423 POLB
NCBI Gene:5423 POLB
OMIM:174760 POLB
UCSC:P06746 POLB
Reference Transcript
Other Identifiers
11725123_a_at
1696_at
17068510
203616_PM_at
203616_at
2339593
234907_PM_x_at
234907_x_at
3096172
3096173
3096175
3096179
3096180
3096181
3096182
3096183
3096184
3096185
3096186
3096187
3096188
3096189
3096190
3096191
3096192
3096193
3096194
3096195
3096196
3096204
3096205
3096206
3096207
3096208
3096209
5423
8146198
A_14_P101242
A_14_P109302
A_14_P109786
A_14_P115835
A_32_P34552
D29013_at
GE497569
GE545386
GO:0001701
GO:0002376
GO:0003677
GO:0003684
GO:0003824
GO:0003887
GO:0003906
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005874
GO:0005876
GO:0006259
GO:0006260
GO:0006261
GO:0006281
GO:0006284
GO:0006287
GO:0006290
GO:0006303
GO:0006310
GO:0006915
GO:0006954
GO:0006974
GO:0007435
GO:0008017
GO:0008092
GO:0008630
GO:0010332
GO:0012501
GO:0016445
GO:0016446
GO:0016740
GO:0016779
GO:0016829
GO:0019899
GO:0032991
GO:0034061
GO:0043226
GO:0045471
GO:0046872
GO:0048535
GO:0048536
GO:0048856
GO:0048872
GO:0051402
GO:0051575
GO:0055093
GO:0071707
GO:0071897
GO:0140078
GO:0140097
HMNXSV003015554
HMNXSV003038040
Hs.241525.0.S1_3p_at
ILMN_1767894
PH_hs_0010659
S82472_at
TC08000326.hg
g4505930_3p_at
Participates
as a component of
as an output of
as an input of
Other forms of this molecule
PolyUb-POLB [nucleoplasm]
Inferred To
polb [nucleoplasm] (Xenopus tropicalis)
polB [nucleoplasm] (Dictyostelium discoideum)
POLB [nucleoplasm] (Bos taurus)
POLB [nucleoplasm] (Canis familiaris)
POLB [nucleoplasm] (Danio rerio)
POLB [nucleoplasm] (Mus musculus)
POLB [nucleoplasm] (Rattus norvegicus)
POLB [nucleoplasm] (Sus scrofa)
Cross References
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ENSEMBL
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
GlyGen
PDB
1ZQP, 9ICJ, 7ICU, 7RBL, 6BTE, 5TB8, 4KLM, 5DB7, 1MQ2, 6PKZ, 3RH4, 5J0S, 3JPR, 5V1I, 4PH5, 8ICK, 4F5O, 5UGO, 6W2M, 6NKV, 5J2J, 7ICN, 4Z6E, 6CRB, 1ZQB, 6BEL, 1ZJN, 3LK9, 5WNZ, 5J0O, 7ICV, 4MFF, 6NL0, 8ICH, 3RH5, 6NKX, 9ICM, 7RBO, 8ICP, 4NY8, 4KLO, 5DB9, 5V1H, 3JPS, 5U8G, 7ICG, 4F5P, 1BPX, 6MR8, 6NKU, 5J2I, 6G2Q, 3RJK, 6BEM, 1ZQA, 1ZJM, 6CRC, 1ZQR, 4O5C, 4PGQ, 4PHA, 9ICC, 5DB6, 4TUS, 7ICQ, 7S9N, 5J0T, 5U8I, 3ISD, 6CPQ, 6UOM, 8ICB, 7ICP, 6NKT, 8ICJ, 4Z6D, 5BOM, 5J2H, 1ZQD, 6CTN, 5WNY, 7RBE, 3C2M, 5J0P, 1ZQQ, 7MZ8, 7RBK, 5TZV, 7ICR, 4O5E, 5DB8, 3JPQ, 1MQ3, 9ICN, 8ICC, 5U8H, 6E3R, 5UGP, 6UOL, 7RBF, 6N2T, 7ICM, 6NKS, 8ICW, 5BOL, 5J2G, 6CTM, 1ZQC, 1BPY, 5WNX, 4F5N, 1ZQT, 7RBM, 6CTW, 4R65, 4UB5, 4M9N, 5EOZ, 9ICF, 6CTL, 7ICS, 5DBA, 4KLD, 4M47, 6N2R, 3ISC, 6E3V, 5VRX, 4TUP, 4RPX, 3MBY, 5J2E, 5VRY, 4Z6C, 4M9G, 1ZQS, 4R66, 7RBN, 7MZ4, 7ICT, 6PH6, 9ICE, 6CTK, 7S9J, 8VF9, 4TUR, 5J29, 8ICM, 5VRW, 7S9M, 8ICV, 8VF8, 4TUQ, 6E3X, 7ICO, 4RPY, 2I9G, 4UAW, 1ZQE, 1BPZ, 3C2L, 6UOK, 6CU9, 4PPX, 5J0Y, 4PHD, 9ICB, 5HHI, 4UB3, 6CTJ, 8ICA, 1ZQI, 9ICW, 4KLJ, 7RBG, 4R63, 8VFE, 4MF8, 4GXJ, 4RQ7, 6N2S, 7ICI, 3ISB, 5DBC, 6DIA, 5VRZ, 3RJI, 9ICO, 4PHE, 4R64, 9ICA, 4UB4, 6CTI, 4MF2, 1ZQH, 8ICE, 4KLL, 5DBB, 7RBH, 4RQ8, 6E3W, 7ICJ, 4GXK, 7S9P, 3RJJ, 8ICY, 8ICL, 5J2F, 2FMQ, 1ZQF, 3C2K, 4M9J, 4O5K, 4MFA, 9ICQ, 5V1F, 5HHH, 8VFI, 7S9K, 1ZQK, 4NM2, 7RBI, 5UGN, 4KLH, 8VFG, 4RQ6, 7ICK, 4NM1, 4YMM, 4UBC, 1ZQG, 3RJG, 8ICS, 6CTV, 6CR4, 5VS4, 6CTX, 4MFC, 9ICP, 4DOC, 4M9L, 4UB2, 7S9L, 4PHP, 1ZQJ, 2P66, 8VFD, 4YMO, 9ICX, 7RBJ, 4KLI, 4GXI, 7S9O, 7ICL, 5U2T, 8ICX, 4YMN, 3RJH, 6CTU, 6CR3, 2FMS, 9ICR, 7MZ0, 9ICG, 4UAZ, 8VFH, 5VS0, 6CTQ, 2ISP, 6CUA, 4O9M, 5TBA, 4KLF, 1ZQM, 8VFA, 5VEZ, 7K97, 9ICT, 4NLK, 5J2C, 5BPC, 8ICU, 6CR9, 5U2R, 5U9H, 3RJE, 5VS2, 4UB1, 7MZ1, 4M9H, 5V1G, 6CUB, 6CTT, 4NLZ, 4DOB, 5J0W, 2ISO, 1ZQL, 4KLG, 8VFF, 8ICG, 9ICY, 7K96, 8ICO, 4UBB, 9ICS, 4NLN, 3RJF, 8ICR, 5V1R, 4RQ5, 6CTO, 7MZ3, 5VS1, 4KLT, 9ICH, 9ICK, 4RQ1, 8VFJ, 6U2O, 6NKY, 8ICF, 5TBB, 1ZQO, 3TFR, 8VFC, 3JPO, 9ICV, 4P2H, 4YN4, 8VFB, 7ICF, 8ICT, 5J2A, 6CR8, 5VS3, 4JWN, 5U2S, 5V1N, 4PGY, 5J0Q, 2FMP, 4UAY, 4DOA, 5J0X, 6CTR, 4RQ2, 3TFS, 1ZQN, 4DO9, 4KLE, 5TB9, 8ICN, 3JPP, 9ICU, 5J2D, 5TBC, 4M2Y, 6CR7, 4KLU, 4RQ4, 5V1P, 6U6B, 3GDX, 4RT2, 5V1J, 9ICI, 6CLY, 7MZ2, 6CR6, 6NKR, 6DIC, 3RH6, 8ICI, 6NKW, 9ICL, 6MR7, 1TV9, 4NXZ, 3JPT, 4KLQ, 2PXI, 4RPZ, 4F5Q, 5J2K, 4LVS, 7ICH, 6PH5, 4Z6F, 5WO0, 4PGX, 6CTP, 1TVA, 4RQ0, 5V1O, 5J0R, 5J0U, 6CR5, 6BTF, 4RT3, 3OGU, 7S9Q, 6NKZ, 3JPN, 6CRH, 4KLS, 8ICQ, 7ICE, 4F5R, 8ICZ, 5J2B, 4JWM, 4RQ3
ZINC - Metabolites
HPA
Pharos - Targets
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (16)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P29144 TPP2  1 0.781 8
 UniProt:P18887 XRCC1  1 0.738 5
 UniProt:Q9NUW8 TDP1  1 0.643 3
 UniProt:O76024 WFS1  3 0.556 3
 UniProt:Q9H5J8 TAF1D  1 0.543 4
 UniProt:P09874 PARP1  4 0.527 2
 UniProt:P49916 LIG3  1 0.527 3
 UniProt:P21953 BCKDHB  8 0.527 2
 UniProt:Q96T60 PNKP  1 0.527 2
 UniProt:Q01831 XPC  5 0.527 2
 UniProt:P0C0S8 H2AC11  11 0.527 2
 UniProt:Q08945 SSRP1  1 0.527 2
 UniProt:Q8IW19 APLF      0.527 2
 UniProt:P12694 BCKDHA  7 0.527 2
 UniProt:Q9Y5B9 SUPT16H  1 0.527 2
 UniProt:P63158  5 0.462 2
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