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Reactome Pathway Database

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KRM:DKK:LRP5/6 [early endosome membrane]

Stable Identifier
R-HSA-5368514
Type
Complex
Species
Homo sapiens
Compartment
early endosome membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
    • Signaling by WNT (Homo sapiens)
      • TCF dependent signaling in response to WNT (Homo sapiens)
        • Negative regulation of TCF-dependent signaling by WNT ligand antagonists (Homo sapiens)
          • DKK promotes clathrin-dependent internalization of LRP6 (Homo sapiens)
            • KRM:DKK:LRP5/6 [early endosome membrane] (Homo sapiens)
Participants
components
  • DKK [early endosome membrane] (Homo sapiens)
  • KRM1/2 [early endosome membrane] (Homo sapiens)
  • LRP5/6 [early endosome membrane] (Homo sapiens)
Participant Of
output
  • DKK promotes clathrin-dependent internalization of LRP6
Inferred To
KRM:DKK:LRP5/6 [early endosome membrane] (Bos taurus)
KRM:DKK:LRP5/6 [early endosome membrane] (Canis familiaris)
KRM:DKK:LRP5/6 [early endosome membrane] (Mus musculus)
KRM:DKK:LRP5/6 [early endosome membrane] (Rattus norvegicus)
KRM:DKK:LRP5/6 [early endosome membrane] (Sus scrofa)
KRM:DKK:LRP5/6 [early endosome membrane] (Xenopus tropicalis)
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