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FZD5 [early endosome membrane]
Stable Identifier
R-HSA-5368467
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
early endosome membrane
Synonyms
Frizzled-5, FZD5_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Homo sapiens)
WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Homo sapiens)
WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [early endosome membrane] (Homo sapiens)
FZD5 [early endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13467 FZD5
Gene Names
FZD5, C2orf31
Chain
signal peptide:1-26, chain:27-585
Reference Genes
BioGPS Gene:7855 FZD5
COSMIC (genes):FZD5 FZD5
CTD Gene:7855 FZD5
dbSNP Gene:7855 FZD5
ENSEMBL:ENSG00000163251 FZD5
ENSEMBL_homo_sapiens_GENE:ENSG00000163251.4 FZD5
HGNC:4043 FZD5
KEGG Gene (Homo sapiens):7855 FZD5
Monarch:7855 FZD5
NCBI Gene:7855 FZD5
OMIM:601723 FZD5
UCSC:Q13467 FZD5
Reference Transcript
RefSeq:NM_003468.3 FZD5
Other Identifiers
11721424_at
11721425_at
11721426_at
11721427_at
11757573_s_at
16907691
206136_PM_at
206136_at
221245_PM_s_at
221245_s_at
2596758
2596760
2596762
2596764
2596765
2596766
2596767
2596768
2596769
2596770
2596771
2596772
2596773
2596775
2596777
2596778
2596779
2596780
2596781
2596782
2596783
34997_r_at
60458_at
77605_at
7855
8058498
89369_at
A_23_P108437
A_23_P397999
A_24_P148503
GE55366
GE81283
GO:0000139
GO:0000578
GO:0001525
GO:0001540
GO:0001944
GO:0002071
GO:0002376
GO:0002726
GO:0004888
GO:0004930
GO:0005515
GO:0005768
GO:0005769
GO:0005794
GO:0005886
GO:0005923
GO:0006351
GO:0006355
GO:0006886
GO:0006914
GO:0007005
GO:0007165
GO:0007166
GO:0007186
GO:0007416
GO:0008285
GO:0008289
GO:0008595
GO:0009986
GO:0012501
GO:0016020
GO:0016055
GO:0017147
GO:0019901
GO:0022414
GO:0023052
GO:0030154
GO:0030182
GO:0030424
GO:0030425
GO:0030669
GO:0031076
GO:0031077
GO:0031410
GO:0031625
GO:0031901
GO:0032729
GO:0032731
GO:0032760
GO:0033077
GO:0034330
GO:0035567
GO:0042813
GO:0042995
GO:0043204
GO:0043226
GO:0044877
GO:0045202
GO:0045944
GO:0048471
GO:0048596
GO:0048856
GO:0060061
GO:0060070
GO:0060089
GO:0060561
GO:0060574
GO:0060670
GO:0060715
GO:0060716
GO:0060718
GO:0071219
GO:1901382
GO:1901524
GO:1903955
GO:2000810
HMNXSV003053473
ILMN_1798971
PH_hs_0001591
PH_hs_0009160
PH_hs_0037748
TC02002714.hg
U43318_at
g13540591_3p_s_at
g4503828_3p_at
Participates
as a component of
WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [early endosome membrane] (Homo sapiens)
Other forms of this molecule
ub-FZD5 [plasma membrane]
FZD5 [clathrin-coated endocytic vesicle membrane]
FZD5 [plasma membrane]
Inferred To
fzd8b [early endosome membrane]
(Danio rerio)
Fzd5 [early endosome membrane]
(Mus musculus)
Fzd5 [early endosome membrane]
(Rattus norvegicus)
fzd8a [early endosome membrane]
(Danio rerio)
Homologues of FZD5 [early endosome membrane]
(Danio rerio)
cfz-2 [early endosome membrane]
(Caenorhabditis elegans)
fzd5 [early endosome membrane]
(Danio rerio)
Ghost homologue of FZD5 [early endosome membrane]
(Gallus gallus)
FZD5 [early endosome membrane]
(Bos taurus)
FZD5 [early endosome membrane]
(Canis familiaris)
FZD5 [early endosome membrane]
(Sus scrofa)
Cross References
RefSeq
NP_003459.2
Guide to Pharmacology - Targets
233
OpenTargets
ENSG00000163251
HPA
ENSG00000163251-FZD5
GeneCards
Q13467
Ensembl
ENSP00000354607
,
ENSG00000163251
,
ENST00000295417
PRO
Q13467
Pharos - Targets
Q13467
Orphanet
24030
PDB
5URY
,
6WW2
,
5URZ
,
6O39
HMDB Protein
HMDBP07701
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