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MRPS6 [mitochondrial inner membrane]
Stable Identifier
R-HSA-5368254
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
28S ribosomal protein S6, mitochondrial, RT06_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Translation (Homo sapiens)
Mitochondrial translation (Homo sapiens)
Mitochondrial translation elongation (Homo sapiens)
55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA at A-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA:GFM1:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
Peptide transfer from P-site to A-site (peptide bond formation) (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA at A-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA:TUFM:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA:TUFM:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA) (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA at P-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA:GFM1:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
Mitochondrial translation initiation (Homo sapiens)
28S subunit:MTIF3 binds MTIF2:GTP, mRNA, and formylMet-tRNA (Homo sapiens)
28S ribosomal subunit:MTIF3 [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit:MTIF3:MTIF2:GTP:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
39S subunit binds 28S subunit:mRNA:fMet-tRNA (Homo sapiens)
28S ribosomal subunit:MTIF3:MTIF2:GTP:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
MTIF3 binds 28S ribosomal subunit (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit:MTIF3 [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
Mitochondrial translation termination (Homo sapiens)
55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA (Homo sapiens)
55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:MRRF [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
Hydrolysis of GTP and dissociation of 28S and 39S subunits (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
MRRF binds 55S ribosome:mRNA:tRNA (Homo sapiens)
55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:MRRF [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA at P-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS6 [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P82932 MRPS6
Gene Names
MRPS6, C21orf101, RPMS6
Chain
chain:1-125
Reference Genes
BioGPS Gene:64968 MRPS6
COSMIC (genes):MRPS6 MRPS6
CTD Gene:64968 MRPS6
dbSNP Gene:64968 MRPS6
ENSEMBL:ENSG00000243927 MRPS6
ENSEMBL_homo_sapiens_GENE:ENSG00000243927.6 MRPS6
HGNC:14051 MRPS6
KEGG Gene (Homo sapiens):64968 MRPS6
Monarch:64968 MRPS6
NCBI Gene:64968 MRPS6
OMIM:611973 MRPS6
UCSC:P82932 MRPS6
Reference Transcript
RefSeq:NM_032476.3 MRPS6
Other Identifiers
11743579_a_at
224919_PM_at
224919_at
3918996
3918997
3918998
3919015
3919022
3919023
3919024
46238_at
64968
A_14_P115764
A_23_P102890
A_24_P365571
GO:0003723
GO:0003735
GO:0005198
GO:0005515
GO:0005737
GO:0005739
GO:0005743
GO:0005763
GO:0005840
GO:0006412
GO:0015935
GO:0019843
GO:0032543
GO:0043226
GO:0043229
GO:0070181
GO:0140053
GO:1990904
HMNXSV003042692
Hs.6945.0.S1_3p_at
ILMN_1723874
Participates
as a component of
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
Inferred To
Mrps6 [mitochondrial inner membrane]
(Mus musculus)
Mrps6 [mitochondrial inner membrane]
(Rattus norvegicus)
mrps-6 [mitochondrial inner membrane]
(Caenorhabditis elegans)
MRPS6 [mitochondrial inner membrane]
(Bos taurus)
MRPS6 [mitochondrial inner membrane]
(Canis familiaris)
MRPS6 [mitochondrial inner membrane]
(Gallus gallus)
MRPS6 [mitochondrial inner membrane]
(Sus scrofa)
mRpS6 [mitochondrial inner membrane]
(Drosophila melanogaster)
mrps6 [mitochondrial inner membrane]
(Danio rerio)
Cross References
RefSeq
NP_115865.1
OpenTargets
ENSG00000243927
GeneCards
P82932
HPA
ENSG00000243927-MRPS6
Ensembl
ENSP00000382250
,
ENST00000399312
,
ENSG00000243927
PRO
P82932
Pharos - Targets
P82932
PDB
6ZSC
,
7QI6
,
6ZSB
,
3J9M
,
6RW4
,
7OG4
,
7A5G
,
7PNX
,
6ZSD
,
6ZSA
,
6NU3
,
7A5I
,
8CST
,
8ANY
,
6ZSE
,
7P2E
,
8CSU
,
7PO0
,
7PNY
,
7PNZ
,
6ZS9
,
6NU2
,
7A5K
,
6VMI
,
7PO1
,
6ZSG
,
6ZM6
,
6ZM5
,
7PO2
,
7PO3
,
8OIR
,
6VLZ
,
8OIS
,
8CSP
,
7QI4
,
8CSQ
,
7L08
,
7QI5
,
8CSR
,
6RW5
,
8CSS
,
7A5F
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