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MRPL39 [mitochondrial inner membrane]
Stable Identifier
R-HSA-5368227
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
39S ribosomal protein L39, mitochondrial, RM39_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Translation (Homo sapiens)
Mitochondrial translation (Homo sapiens)
Mitochondrial translation elongation (Homo sapiens)
55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA at A-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA:GFM1:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
Peptide transfer from P-site to A-site (peptide bond formation) (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA at A-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA:TUFM:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA:TUFM:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA) (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA at P-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA:GFM1:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
Mitochondrial translation initiation (Homo sapiens)
39S subunit binds 28S subunit:mRNA:fMet-tRNA (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
Mitochondrial translation termination (Homo sapiens)
55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA (Homo sapiens)
55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:MRRF [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
Hydrolysis of GTP and dissociation of 28S and 39S subunits (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
MRRF binds 55S ribosome:mRNA:tRNA (Homo sapiens)
55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:MRRF [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA at P-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPL39 [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NYK5 MRPL39
Gene Names
MRPL39, C21orf92, MRPL5, RPML5, MSTP003, PRED22
Chain
chain:1-338
Reference Genes
BioGPS Gene:54148 MRPL39
COSMIC (genes):MRPL39 MRPL39
CTD Gene:54148 MRPL39
dbSNP Gene:54148 MRPL39
ENSEMBL:ENSG00000154719 MRPL39
ENSEMBL_homo_sapiens_GENE:ENSG00000154719.14 MRPL39
HGNC:14027 MRPL39
KEGG Gene (Homo sapiens):54148 MRPL39
Monarch:54148 MRPL39
NCBI Gene:54148 MRPL39
OMIM:611845 MRPL39
UCSC:Q9NYK5 MRPL39
Reference Transcript
RefSeq:NM_080794.3 MRPL39
RefSeq:NM_017446.3 MRPL39
RefSeq:XM_006724026.3 MRPL39
Other Identifiers
11717459_a_at
11741883_a_at
16924523
218558_PM_s_at
218558_s_at
3927126
3927128
3927130
3927135
3927136
3927137
3927139
3927140
3927141
3927142
3927143
3927144
3927145
54148
54688_at
8069620
GE55502
GO:0000166
GO:0003723
GO:0005739
GO:0005743
GO:0005761
GO:0005762
GO:0005840
GO:0032543
GO:0043226
GO:0140053
GO:1990904
HMNXSV003010082
HMNXSV003048694
ILMN_1726391
ILMN_1778730
PH_hs_0025127
PH_hs_0035940
TC21000338.hg
g8394038_3p_s_at
Participates
as a component of
39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
Inferred To
MRPL39 [mitochondrial inner membrane]
(Bos taurus)
MRPL39 [mitochondrial inner membrane]
(Canis familiaris)
MRPL39 [mitochondrial inner membrane]
(Gallus gallus)
MRPL39 [mitochondrial inner membrane]
(Sus scrofa)
mrpl-39 [mitochondrial inner membrane]
(Caenorhabditis elegans)
mrpl39 [mitochondrial inner membrane]
(Danio rerio)
mRpL39 [mitochondrial inner membrane]
(Drosophila melanogaster)
Mrpl39 [mitochondrial inner membrane]
(Mus musculus)
Mrpl39 [mitochondrial inner membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_542984.2
,
XP_006724089.1
,
NP_059142.2
OpenTargets
ENSG00000154719
GeneCards
Q9NYK5
HPA
ENSG00000154719-MRPL39
Ensembl
ENST00000352957
,
ENST00000307301
,
ENSP00000305682
,
ENSP00000284967
,
ENSG00000154719
PRO
Q9NYK5
Pharos - Targets
Q9NYK5
PDB
7OF4
,
7OID
,
6VLZ
,
7OIC
,
7PO4
,
7OG4
,
7QH7
,
7OF2
,
8ANY
,
7OF3
,
7ODR
,
8QSJ
,
6ZS9
,
7OF0
,
7PD3
,
7OF7
,
7OI9
,
6NU3
,
6ZSG
,
7OI8
,
7OF6
,
7QI4
,
6ZSE
,
7L08
,
3J9M
,
7A5F
,
6ZSD
,
7OI7
,
6ZSC
,
7ODT
,
7OI6
,
6ZSB
,
7ODS
,
7A5K
,
6ZSA
,
7OIB
,
7QH6
,
8OIT
,
7OIA
,
7A5J
,
7QI6
,
8OIR
,
3J7Y
,
7A5I
,
6NU2
,
7A5H
,
7QI5
,
6ZM6
,
6VMI
,
7O9M
,
7L20
,
5OOL
,
6I9R
,
7A5G
,
6ZM5
,
8PK0
,
7OIE
,
7O9K
,
7OF5
,
5OOM
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