Reactome | AURKAIP1 [mitochondrial inner membrane]

AURKAIP1 [mitochondrial inner membrane]

Stable Identifier

R-HSA-5368203

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Aurora kinase A-interacting protein, AKIP_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NWT8 AURKAIP1

Gene Names

AURKAIP1, AIP, AKIP, MRPS38

Chain

chain:1-199

Reference Genes

BioGPS Gene:54998 AURKAIP1

COSMIC (genes):AURKAIP1 AURKAIP1

CTD Gene:54998 AURKAIP1

dbSNP Gene:54998 AURKAIP1

ENSEMBL:ENSG00000175756.14 AURKAIP1

HGNC:24114 AURKAIP1

KEGG Gene (Homo sapiens):54998 AURKAIP1

Monarch:54998 AURKAIP1

NCBI Gene:54998 AURKAIP1

OMIM:609183 AURKAIP1

UCSC:Q9NWT8 AURKAIP1

Reference Transcript

Other Identifiers

0004230286

0101410300

11715276_s_at

11715277_s_at

11715278_s_at

16680274

218580_PM_x_at

218580_x_at

225552_PM_x_at

225552_x_at

228800_3p_x_at

228800_PM_x_at

228800_x_at

2391515

2391516

2391517

2391519

2391520

2391521

2391525

2391526

2391527

2391528

2391529

2391530

2391531

4041962

4041963

4041964

4041965

4041966

4041967

4041968

4041972

4041973

4041974

4041975

4041977

4041978

54998

75854_at

76844_at

7911532

8039923

88103_s_at

A_23_P103885

A_33_P3240518

GE82243

GO:0000278

GO:0005515

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005739

GO:0005743

GO:0005763

GO:0005840

GO:0006397

GO:0016071

GO:0032543

GO:0032991

GO:0043226

GO:0043231

GO:0045839

GO:0045862

GO:0140014

GO:0140053

GO:1990904

HMNXSV003017965

Hs.76239.1.S1_3p_a_at

Hs.76239.2.A1_3p_at

Hs.76239.2.A1_3p_s_at

Hs.76239.2.A1_3p_x_at

Hs.76239.3.A1_3p_x_at

ILMN_1700793

ILMN_1768396

PH_hs_0028974

PH_hs_0030744

TC01002094.hg

TC01005207.hg

Participates

as a component of

28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)

Inferred To

LOC549720 [mitochondrial inner membrane] (Xenopus tropicalis)

Aurkaip1 [mitochondrial inner membrane] (Mus musculus)

AURKAIP1 [mitochondrial inner membrane] (Bos taurus)

AURKAIP1 [mitochondrial inner membrane] (Canis familiaris)

AURKAIP1 [mitochondrial inner membrane] (Danio rerio)

AURKAIP1 [mitochondrial inner membrane] (Gallus gallus)

AURKAIP1 [mitochondrial inner membrane] (Sus scrofa)

Ghost homologue of AURKAIP1 [mitochondrial inner membrane] (Drosophila melanogaster)

Ghost homologue of AURKAIP1 [mitochondrial inner membrane] (Rattus norvegicus)

2O16 [mitochondrial inner membrane] (Caenorhabditis elegans)

Cross References

ZINC - Investigational

AKIP_HUMAN

RefSeq

NP_001120701.1, NP_001120702.1, NP_060370.1

OpenTargets

ENSG00000175756

HPA

ENSG00000175756-AURKAIP1

ZINC - Substances

AKIP_HUMAN

GeneCards

Q9NWT8

Ensembl

ENSP00000340656, ENST00000378853, ENSP00000342676, ENSP00000319778, ENST00000338370, ENST00000321751, ENSG00000175756, ENST00000338338, ENSP00000368130

ZINC target

Q9NWT8

PRO

Q9NWT8

Pharos - Targets

Q9NWT8

ZINC - Predictions - Purchasable

AKIP_HUMAN

PDB

6ZSG, 6VMI, 6ZM6, 7A5F, 6ZSC, 6NU3, 6ZM5, 7A5K, 7L08, 6NU2, 6ZSB, 6ZSD, 3J9M, 6ZS9, 6VLZ, 7A5I, 6RW4, 6RW5, 7OG4, 6ZSA, 6ZSE, 7A5G

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8TB40 ABHD4	1	ABHD4 [endoplasmic reticulum membrane] (R-HSA-5694582)	0.556	3
UniProt:O14965 AURKA	6	SUMO1-K258-AURKA [cytosol] (R-HSA-4655367) p-T288-AURKA [nucleoplasm] (R-HSA-6805089) AURKA [nucleoplasm] (R-HSA-4655443) PolyUb-AURKA [cytosol] (R-HSA-8854040) AURKA [cytosol] (R-HSA-174254) p-T288-AURKA [cytosol] (R-HSA-2574832)	0.524	2

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