Reactome | AURKAIP1 [mitochondrial inner membrane]

AURKAIP1 [mitochondrial inner membrane]

Stable Identifier

R-HSA-5368203

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Aurora kinase A-interacting protein, AKIP_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NWT8 AURKAIP1

Gene Names

AURKAIP1, AIP, AKIP, MRPS38

Chain

chain:1-199

Reference Genes

BioGPS Gene:54998 AURKAIP1

COSMIC (genes):AURKAIP1 AURKAIP1

CTD Gene:54998 AURKAIP1

dbSNP Gene:54998 AURKAIP1

ENSEMBL:ENSG00000175756 AURKAIP1

ENSEMBL_homo_sapiens_GENE:ENSG00000175756.14 AURKAIP1

HGNC:24114 AURKAIP1

KEGG Gene (Homo sapiens):54998 AURKAIP1

Monarch:54998 AURKAIP1

NCBI Gene:54998 AURKAIP1

OMIM:609183 AURKAIP1

UCSC:Q9NWT8 AURKAIP1

Reference Transcript

Other Identifiers

11715276_s_at

11715277_s_at

11715278_s_at

16680274

218580_PM_x_at

218580_x_at

225552_PM_x_at

225552_x_at

228800_3p_x_at

228800_PM_x_at

228800_x_at

2391515

2391516

2391517

2391519

2391520

2391521

2391525

2391526

2391527

2391528

2391529

2391530

2391531

4041962

4041963

4041964

4041965

4041966

4041967

4041968

4041972

4041973

4041974

4041975

4041977

4041978

54998

75854_at

76844_at

7911532

8039923

88103_s_at

A_23_P103885

A_33_P3240518

GE82243

GO:0000278

GO:0005515

GO:0005634

GO:0005654

GO:0005739

GO:0005743

GO:0005759

GO:0005763

GO:0005840

GO:0032543

GO:0043226

GO:0043231

GO:0045839

GO:0045862

GO:0140014

GO:0140053

GO:1990904

HMNXSV003017965

Hs.76239.1.S1_3p_a_at

Hs.76239.2.A1_3p_at

Hs.76239.2.A1_3p_s_at

Hs.76239.2.A1_3p_x_at

Hs.76239.3.A1_3p_x_at

ILMN_1768396

PH_hs_0028974

PH_hs_0030744

TC01002094.hg

TC01005207.hg

Participates

as a component of

28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)

Inferred To

Aurkaip1 [mitochondrial inner membrane] (Mus musculus)

AURKAIP1 [mitochondrial inner membrane] (Bos taurus)

AURKAIP1 [mitochondrial inner membrane] (Canis familiaris)

AURKAIP1 [mitochondrial inner membrane] (Danio rerio)

AURKAIP1 [mitochondrial inner membrane] (Gallus gallus)

AURKAIP1 [mitochondrial inner membrane] (Sus scrofa)

Ghost homologue of AURKAIP1 [mitochondrial inner membrane] (Drosophila melanogaster)

Ghost homologue of AURKAIP1 [mitochondrial inner membrane] (Rattus norvegicus)

2O16 [mitochondrial inner membrane] (Caenorhabditis elegans)

Cross References

ZINC - Investigational

AKIP_HUMAN

RefSeq

NP_001120702.1, NP_001120701.1, NP_060370.1

OpenTargets

ENSG00000175756

HPA

ENSG00000175756-AURKAIP1

ZINC - Substances

AKIP_HUMAN

GeneCards

Q9NWT8

ZINC target

Q9NWT8

Ensembl

ENSP00000342676, ENSP00000368130, ENST00000378853, ENST00000338370, ENSP00000340656, ENST00000321751, ENSG00000175756, ENSP00000319778, ENST00000338338

PRO

Q9NWT8

Pharos - Targets

Q9NWT8

ZINC - Predictions - Purchasable

AKIP_HUMAN

PDB

7P2E, 7A5I, 8OIS, 7PNX, 3J9M, 6RW4, 8CSQ, 7A5G, 7QI4, 7OG4, 6VMI, 6NU3, 6ZM6, 8OIR, 6ZS9, 6ZSA, 8CSS, 7A5K, 7PO0, 6ZSB, 7QI6, 7PNY, 8CSR, 7QI5, 6RW5, 6ZSD, 8ANY, 7PO2, 6ZSC, 8CSU, 7PO1, 6VLZ, 8CST, 7PNZ, 6ZM5, 6ZSE, 7A5F, 7PO3, 7L08, 6ZSG, 6NU2

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8TB40 ABHD4	1	ABHD4 [endoplasmic reticulum membrane] (R-HSA-5694582)	0.556	3
UniProt:O14965 AURKA	6	SUMO1-K258-AURKA [cytosol] (R-HSA-4655367) PolyUb-AURKA [cytosol] (R-HSA-8854040) p-T288-AURKA [nucleoplasm] (R-HSA-6805089) AURKA [nucleoplasm] (R-HSA-4655443) AURKA [cytosol] (R-HSA-174254) p-T288-AURKA [cytosol] (R-HSA-2574832)	0.524	2

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