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CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-5362445
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
Indian hedgehog protein N product, IHH, IHH_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Hedgehog (Homo sapiens)
Hedgehog ligand biogenesis (Homo sapiens)
HHAT palmitoylates Hh N-terminal fragment (Homo sapiens)
Hh-Np [endoplasmic reticulum lumen] (Homo sapiens)
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [endoplasmic reticulum lumen] (Homo sapiens)
Hh-Np traffics to the plasma membrane (Homo sapiens)
Hh-Np [endoplasmic reticulum lumen] (Homo sapiens)
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q14623 IHH
Gene Names
IHH, Indian hedgehog
Chain
signal peptide:1-27, chain:28-411, chain:28-202
Reference Genes
BioGPS Gene:3549 IHH
COSMIC (genes):IHH IHH
CTD Gene:3549 IHH
dbSNP Gene:3549 IHH
ENSEMBL:ENSG00000163501 IHH
ENSEMBL_homo_sapiens_GENE:ENSG00000163501.7 IHH
HGNC:5956 IHH
KEGG Gene (Homo sapiens):3549 IHH
Monarch:3549 IHH
NCBI Gene:3549 IHH
OMIM:600726 IHH
UCSC:Q14623 IHH
Reference Transcript
RefSeq:NM_002181.3 IHH
Other Identifiers
11725278_at
11725279_at
16908552
215420_PM_at
215420_at
229358_PM_at
229358_at
2599799
2599800
2599801
2599806
2599807
2599813
2599814
2599815
2599816
2599817
2599818
2599819
2599820
2599822
34618_at
3549
8059067
89808_at
899_at
A_33_P3338698
GE508441
GO:0000139
GO:0001501
GO:0001503
GO:0001569
GO:0001649
GO:0001701
GO:0001708
GO:0001763
GO:0001944
GO:0001947
GO:0002053
GO:0002062
GO:0002376
GO:0003382
GO:0003406
GO:0003413
GO:0003824
GO:0005113
GO:0005509
GO:0005515
GO:0005576
GO:0005615
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0006029
GO:0006351
GO:0006355
GO:0006508
GO:0007155
GO:0007224
GO:0007267
GO:0007275
GO:0007389
GO:0008233
GO:0008283
GO:0008284
GO:0009612
GO:0009880
GO:0010468
GO:0012501
GO:0016020
GO:0016539
GO:0016540
GO:0016740
GO:0016787
GO:0022414
GO:0023052
GO:0030154
GO:0030198
GO:0030312
GO:0030704
GO:0031012
GO:0031016
GO:0032331
GO:0032355
GO:0032967
GO:0033085
GO:0033088
GO:0033089
GO:0035264
GO:0035988
GO:0040008
GO:0042733
GO:0043010
GO:0043066
GO:0043226
GO:0045453
GO:0045880
GO:0045944
GO:0046638
GO:0046639
GO:0046872
GO:0048074
GO:0048469
GO:0048557
GO:0048596
GO:0048666
GO:0048731
GO:0048745
GO:0048856
GO:0050679
GO:0051216
GO:0051604
GO:0060135
GO:0060220
GO:0060323
GO:0061053
GO:0072498
GO:0090136
GO:0097264
GO:0097421
GO:0140096
GO:0140853
GO:1901135
HMNXSV003015026
Hs.115274.0.A1_3p_at
Hs.69351.0.S1_3p_at
ILMN_1801953
L38517_at
PH_hs_0038474
TC02002786.hg
Participates
as a candidate of
Hh-Np [endoplasmic reticulum lumen] (Homo sapiens)
Other forms of this molecule
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [extracellular region]
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [plasma membrane]
ub-N4glycoAsn-IHH(203-411) [endoplasmic reticulum lumen]
ub-N4glycoAsn-IHH(203-411) [cytosol]
2xHC-IHH(28-411) [endoplasmic reticulum lumen]
N4glycoAsn-IHH(203-411) [endoplasmic reticulum lumen]
CHOL-IHH(28-202) [endoplasmic reticulum lumen]
N4glycoAsn-2xHC-IHH(28-411) [endoplasmic reticulum lumen]
IHH [extracellular region]
Inferred To
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [endoplasmic reticulum lumen]
(Bos taurus)
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [endoplasmic reticulum lumen]
(Danio rerio)
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [endoplasmic reticulum lumen]
(Drosophila melanogaster)
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [endoplasmic reticulum lumen]
(Gallus gallus)
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [endoplasmic reticulum lumen]
(Mus musculus)
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [endoplasmic reticulum lumen]
(Sus scrofa)
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [endoplasmic reticulum lumen]
(Xenopus tropicalis)
Ihh [endoplasmic reticulum lumen]
(Rattus norvegicus)
IHH [endoplasmic reticulum lumen]
(Canis familiaris)
Modified Residues
Name
glycine cholesterol ester at 202
Coordinate
202
PsiMod Name
glycine cholesterol ester [MOD:00314]
PsiMod Definition
A protein modification that effectively converts a glycine residue to glycine cholesterol ester.
Name
N-palmitoyl-L-cysteine at 28
Coordinate
28
PsiMod Name
N-palmitoyl-L-cysteine [MOD:00069]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to N-palmitoyl-L-cysteine.
Cross References
RefSeq
NP_002172.2
OpenTargets
ENSG00000163501
HPA
ENSG00000163501-IHH
GeneCards
Q14623
Ensembl
ENSP00000295731
,
ENSG00000163501
,
ENST00000295731
PRO
Q14623
Pharos - Targets
Q14623
Orphanet
16250
PDB
3K7I
,
3K7J
,
3K7G
,
3N1F
,
3N1O
,
3K7H
,
3N1M
,
3N1P
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BWV1 BOC
1
BOC [plasma membrane]
(R-HSA-445450)
0.558
2
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