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NOTUM [extracellular region]
Stable Identifier
R-HSA-5362370
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Hedgehog (Homo sapiens)
Hedgehog ligand biogenesis (Homo sapiens)
Release of Hh-Np from the secreting cell (Homo sapiens)
NOTUM releases Hh-Np:GPC5 from the plasma membrane (Homo sapiens)
NOTUM [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6P988 NOTUM
Gene Names
NOTUM, OK/SW-CL.30
Chain
signal peptide:1-19, chain:20-496
Reference Genes
BioGPS Gene:147111 NOTUM
COSMIC (genes):NOTUM NOTUM
CTD Gene:147111 NOTUM
dbSNP Gene:147111 NOTUM
ENSEMBL:ENSG00000185269 NOTUM
HGNC:27106 NOTUM
KEGG Gene (Homo sapiens):147111 NOTUM
Monarch:147111 NOTUM
NCBI Gene:147111 NOTUM
OMIM:609847 NOTUM
UCSC:Q6P988 NOTUM
Reference Transcript
RefSeq:NM_178493.5 NOTUM
Other Identifiers
0002680731
11723126_at
11723127_x_at
147111
16850047
228649_at
3774476
3774477
3774478
3774479
3774480
3774481
3774484
3774485
3774486
3774488
3774492
3774493
3774494
3774495
3774496
3774497
3774498
4040412
4040413
4040415
4040416
4040417
4040418
4040424
4040425
4040426
4040427
4040428
4040429
4040430
4040433
4040434
4040435
4040436
4040437
8019334
89757_at
A_23_P101007
A_33_P3234635
A_33_P3257125
GE541674
GO:0003674
GO:0004629
GO:0005515
GO:0005575
GO:0005576
GO:0005622
GO:0005737
GO:0005783
GO:0005788
GO:0006464
GO:0007165
GO:0007267
GO:0008150
GO:0009056
GO:0016055
GO:0016787
GO:0030178
GO:0043226
GO:0043687
GO:0044267
GO:0052689
GO:0090090
GO:1990697
GO:1990699
Hs.106137.0.S1_3p_at
ILMN_1744455
ILMN_2166275
PH_hs_0005908
TC17001968.hg
Other forms of this molecule
p-NOTUM [endoplasmic reticulum lumen]
NOTUM [endoplasmic reticulum lumen]
Inferred To
NOTUM [extracellular region] (Canis familiaris)
NOTUM [extracellular region] (Sus scrofa)
notum1a [extracellular region] (Danio rerio)
Notum [extracellular region] (Drosophila melanogaster)
Notum [extracellular region] (Mus musculus)
Cross References
RefSeq
NP_848588.3
Target Pathogen
5b354852be737e166372e73b
OpenTargets
ENSG00000185269
GeneCards
Q6P988
HPA
ENSG00000185269-NOTUM
Ensembl
ENSP00000387310
,
ENST00000409678
,
ENSG00000185269
PRO
Q6P988
PDB
4UZ9
,
6T2K
,
6TR5
,
4UZA
,
6YV2
,
6TR7
,
6TR6
,
6YV0
,
4UYU
,
4UZ1
,
6R8Q
,
4UZ6
,
6R8P
,
4UZ5
,
4UYW
,
6R8R
,
6T2H
,
4UZ7
,
4UYZ
,
4WBH
,
6YV4
,
6YUW
,
6YUY
,
4UZL
,
4UZQ
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8N720 ZNF655
1
ZNF655 [nucleoplasm]
(R-HSA-2127575)
0.556
3
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