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MLH1:PMS2:MSH2:MSH3:ATP:PCNA:DNA containing IDL of 2 bases or more [nucleoplasm]
Stable Identifier
R-HSA-5358523
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
MutSbeta:MutSalpha:ATP:PCNA:DNA containing 1-2 base IDL
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
Mismatch Repair (Homo sapiens)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) (Homo sapiens)
MLH1:PMS2 makes single strand incision near insertion/deletion loop of 2 bases or more (Homo sapiens)
MLH1:PMS2:MSH2:MSH3:ATP:PCNA:DNA containing IDL of 2 bases or more [nucleoplasm] (Homo sapiens)
MSH2:MSH3 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Homo sapiens)
MLH1:PMS2:MSH2:MSH3:ATP:PCNA:DNA containing IDL of 2 bases or more [nucleoplasm] (Homo sapiens)
Participants
components
DNA containing IDL of 2 or more bases [nucleoplasm]
MLH1:PMS2 [nucleoplasm]
(Homo sapiens)
MSH2:MSH3:ATP [nucleoplasm]
(Homo sapiens)
PCNA homotrimer [nucleoplasm]
(Homo sapiens)
Participates
as an output of
MSH2:MSH3 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Homo sapiens)
as an input of
MLH1:PMS2 makes single strand incision near insertion/deletion loop of 2 bases or more (Homo sapiens)
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