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DPH6 [cytosol]
Stable Identifier
R-HSA-5358469
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
diphthamide biosynthesis protein 6, diphthine--ammonia ligase
Locations in the PathwayBrowser for interactor UniProt:P43119 PTGIR
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Homo sapiens)
Synthesis of diphthamide-EEF2 (Homo sapiens)
DPH6 ligates ammonium to diphthine-EEF2 (Homo sapiens)
DPH6 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7L8W6 DPH6
Gene Names
DPH6, ATPBD4
Chain
chain:1-267
Reference Genes
BioGPS Gene:89978 DPH6
COSMIC (genes):DPH6 DPH6
CTD Gene:89978 DPH6
dbSNP Gene:89978 DPH6
ENSEMBL:ENSG00000134146 DPH6
ENSEMBL_homo_sapiens_GENE:ENSG00000134146.12 DPH6
HGNC:30543 DPH6
KEGG Gene (Homo sapiens):89978 DPH6
Monarch:89978 DPH6
NCBI Gene:89978 DPH6
OMIM:618391 DPH6
UCSC:Q7L8W6 DPH6
Reference Transcript
RefSeq:NM_001141972.1 DPH6
RefSeq:NM_080650.3 DPH6
Other Identifiers
11733688_at
11740090_at
1560404_PM_a_at
1560404_a_at
16807080
238662_PM_at
238662_at
3617939
3617940
3617941
3617942
3617943
3617945
3617951
3617954
3617956
3617966
3617967
3617974
3617975
3617976
3617978
79283_at
7987369
89978
A_23_P77135
A_33_P3262416
GE522358
GO:0000166
GO:0002181
GO:0003824
GO:0005524
GO:0005829
GO:0016874
GO:0017178
GO:0017183
GO:0036211
HMNXSV003056211
HMNXSV003056897
Hs.149176.0.A1_3p_at
Hs2.212817.1.S1_3p_s_at
ILMN_1782085
ILMN_2140207
PH_hs_0039538
TC15001205.hg
Inferred To
Dph6 [cytosol]
(Mus musculus)
Dph6 [cytosol]
(Rattus norvegicus)
dph-6 [cytosol]
(Caenorhabditis elegans)
dph6 [cytosol]
(Xenopus tropicalis)
Dmel\CG1578 [cytosol]
(Drosophila melanogaster)
mug71 [cytosol]
(Schizosaccharomyces pombe)
DPH6 [cytosol]
(Bos taurus)
DPH6 [cytosol]
(Canis familiaris)
DPH6 [cytosol]
(Dictyostelium discoideum)
DPH6 [cytosol]
(Gallus gallus)
DPH6 [cytosol]
(Saccharomyces cerevisiae)
DPH6 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_001135444.1
,
NP_542381.1
OpenTargets
ENSG00000134146
GeneCards
Q7L8W6
HPA
ENSG00000134146-DPH6
Ensembl
ENSG00000134146
,
ENST00000440392
,
ENSP00000256538
,
ENST00000256538
,
ENSP00000406976
PRO
Q7L8W6
Pharos - Targets
Q7L8W6
HMDB Protein
HMDBP11712
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P54219 SLC18A1
1
SLC18A1 [clathrin-sculpted monoamine transport vesicle membrane]
(R-HSA-444153)
0.527
2
UniProt:O75173 ADAMTS4
4
ADAMTS4 [extracellular region]
(R-HSA-2533998)
ADAMTS4 [endoplasmic reticulum lumen]
(R-HSA-5173253)
glc-fuc-ADAMTS4 [endoplasmic reticulum lumen]
(R-HSA-5172994)
O-fuc-ADAMTS4 [endoplasmic reticulum lumen]
(R-HSA-5173144)
0.527
2
UniProt:P30550 GRPR
1
GRPR [plasma membrane]
(R-HSA-375363)
0.527
2
UniProt:Q5TF39 MFSD4B
1
NAGLT1 [plasma membrane]
(R-HSA-5216212)
0.527
2
UniProt:P43119 PTGIR
1
PTGIR [plasma membrane]
(R-HSA-391834)
0.527
2
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