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DPH3 [cytosol]
Stable Identifier
R-HSA-5358364
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
diphthamide biosynthesis protein 3, DPH3 homolog
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Gamma carboxylation, hypusine formation and arylsulfatase activation (Homo sapiens)
Synthesis of diphthamide-EEF2 (Homo sapiens)
DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Homo sapiens)
DPH1:DPH2:DPH3 [cytosol] (Homo sapiens)
DPH3 [cytosol] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
14980502
Characterisation of an evolutionary conserved protein interacting with the putative guanine nucleotide exchange factor DelGEF and modulating secretion
Sjölinder, M
,
Uhlmann, J
,
Ponstingl, H
Exp. Cell Res.
2004
14527407
Retroviral insertional mutagenesis identifies a small protein required for synthesis of diphthamide, the target of bacterial ADP-ribosylating toxins
Liu, S
,
Leppla, SH
Mol. Cell
2003
External Reference Information
External Reference
UniProt:Q96FX2 DPH3
Gene Names
DPH3, DESR1, ZCSL2
Chain
chain:1-82
Reference Genes
BioGPS Gene:285381 DPH3
COSMIC (genes):DPH3 DPH3
CTD Gene:285381 DPH3
dbSNP Gene:285381 DPH3
ENSEMBL:ENSG00000154813 DPH3
HGNC:27717 DPH3
KEGG Gene (Homo sapiens):285381 DPH3
Monarch:285381 DPH3
NCBI Gene:285381 DPH3
OMIM:608959 DPH3
UCSC:Q96FX2 DPH3
Reference Transcript
RefSeq:NM_206831.2 DPH3
RefSeq:NM_001047434.2 DPH3
Other Identifiers
0006900022
11733037_a_at
11733038_x_at
11733039_a_at
11733040_a_at
16951298
225195_at
225200_at
2664612
2664613
2664614
2664615
2664616
2664617
2664618
2664619
2664620
2664621
2664622
2664624
2664626
2664627
2664628
285381
2JR7
35287
3893035
44370_at
45320_at
65776_at
8085660
A0A024R2P5
A_23_P69188
A_24_P225907
AAH10181
AK022970
BC010181
CCDS2629
CCDS43058
CH471055
DPH3
DPH3-202
DPH3-204
EAW64268
EAW64269
ENSG00000154813
ENSP00000373285
ENSP00000419599
ENST00000383775
ENST00000383775.4
ENST00000488423
ENST00000488423.1
EntrezGene:285381
EntrezGene:DPH3
GO:0002098
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006399
GO:0006412
GO:0006464
GO:0006810
GO:0008150
GO:0009058
GO:0015031
GO:0017183
GO:0034641
GO:0043167
GO:0043226
GO:0046872
GO:0050709
GO:0051099
HGNC:27717
HPA035287
Hs.264915.0.S1_3p_at
Hs.264915.0.S2_3p_at
ILMN_1679912
ILMN_2261973
ILMN_2349610
IPR007872
IPR036671
MIM:608959
NM_001047434
NM_206831
NP_001040899
NP_996662
PF05207
PH_hs_0035886
TC03001215.hg
UPI000006D340
UPI0000469911
ZCSL2
Participant Of
hasComponent
DPH1:DPH2:DPH3 [cytosol]
Inferred To
DPH3 [cytosol] (Caenorhabditis elegans)
DPH3 [cytosol] (Canis familiaris)
DPH3 [cytosol] (Danio rerio)
DPH3 [cytosol] (Dictyostelium discoideum)
DPH3 [cytosol] (Drosophila melanogaster)
DPH3 [cytosol] (Mus musculus)
DPH3 [cytosol] (Plasmodium falciparum)
DPH3 [cytosol] (Rattus norvegicus)
DPH3 [cytosol] (Saccharomyces cerevisiae)
DPH3 [cytosol] (Schizosaccharomyces pombe)
DPH3 [cytosol] (Sus scrofa)
DPH3 [cytosol] (Xenopus tropicalis)
Cross References
RefSeq
NP_001040899.1
,
NP_996662.1
OpenTargets
ENSG00000154813
GeneCards
Q96FX2
PRO
Q96FX2
PDB
2JR7
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