K63-deubiquitination of RIP1 abolishes its ability to activate NFkB upon TNF-alpha stimulation and leads to the formation of the cytosolic caspase-8 containing complex II and subsequent apoptosis.
Harhaj, EW, Dixit, VM
Hou, X, Wang, L, Zhang, L, Pan, X, Zhao, W
O'Donnell, MA, Hase, H, Legarda, D, Ting, AT
Moquin, DM, McQuade, T, Chan, FK
Mahul-Mellier, AL, Pazarentzos, E, Datler, C, Iwasawa, R, AbuAli, G, Lin, B, Grimm, S
Xu, G, Tan, X, Wang, H, Sun, W, Shi, Y, Burlingame, S, Gu, X, Cao, G, Zhang, T, Qin, J, Yang, J
Enesa, K, Zakkar, M, Chaudhury, H, Luong, le A, Rawlinson, L, Mason, JC, Haskard, DO, Dean, JL, Evans, PC
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