Reactome | CUL7 [cytosol]

CUL7 [cytosol]

Stable Identifier

R-HSA-535534

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Cullin-7, CUL7_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P04637%20TP53

Expand all

Cellular responses to stimuli (Homo sapiens)

- Cellular responses to stress (Homo sapiens)
  - Unfolded Protein Response (UPR) (Homo sapiens)
    - IRE1alpha activates chaperones (Homo sapiens)
      - XBP1(S) activates chaperone genes (Homo sapiens)
        
        Expression of Cullin-7 (Homo sapiens)
        
        CUL7 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q14999 CUL7

Gene Names

CUL7, KIAA0076

Chain

chain:1-1698

Reference Genes

BioGPS Gene:9820 CUL7

COSMIC (genes):CUL7 CUL7

CTD Gene:9820 CUL7

dbSNP Gene:9820 CUL7

ENSEMBL:ENSG00000044090 CUL7

ENSEMBL_homo_sapiens_GENE:ENSG00000044090.13 CUL7

HGNC:21024 CUL7

KEGG Gene (Homo sapiens):9820 CUL7

Monarch:9820 CUL7

NCBI Gene:9820 CUL7

OMIM:609577 CUL7

UCSC:Q14999 CUL7

Reference Transcript

Other Identifiers

11721385_a_at

11721386_s_at

11747908_s_at

17019287

203558_3p_at

203558_PM_at

203558_at

241747_PM_s_at

241747_s_at

2907777

2907782

2954356

2954357

2954360

2954361

2954362

2954364

2954365

2954367

2954368

2954370

2954371

2954372

2954373

2954374

2954377

2954378

2954381

2954384

2954385

2954387

2954389

2954390

2954392

2954393

2954396

2954397

2954398

2954401

2954403

2954408

2954409

2954410

2954411

2954413

2954416

2954417

2954418

2954421

2954422

2954424

36084_PM_at

36084_at

53104_r_at

8126486

91553_at

9820

A_23_P19348

D38548_at

GE57192

GE58624

GO:0000226

GO:0000278

GO:0000281

GO:0000910

GO:0001570

GO:0001837

GO:0001890

GO:0005515

GO:0005634

GO:0005680

GO:0005737

GO:0005794

GO:0005813

GO:0005815

GO:0005829

GO:0005856

GO:0006508

GO:0006511

GO:0007010

GO:0007030

GO:0007088

GO:0016567

GO:0030154

GO:0030163

GO:0031461

GO:0031467

GO:0031625

GO:0036211

GO:0043226

GO:0048471

GO:0048856

GO:0050775

GO:0140014

GO:1990393

HMNXSV003031196

ILMN_1672393

PH_hs_0025126

TC06001742.hg

g7661893_3p_at

g7661893_3p_s_at

g7661893_3p_x_at

Participates

as a component of

as an output of

Expression of Cullin-7 (Homo sapiens)

Inferred To

Cul7 [cytosol] (Mus musculus)

Cul7 [cytosol] (Rattus norvegicus)

cul9 [cytosol] (Xenopus tropicalis)

CUL7 [cytosol] (Bos taurus)

CUL7 [cytosol] (Canis familiaris)

CUL7 [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_001161842.1, NP_055595.2

OpenTargets

ENSG00000044090

GeneCards

Q14999

HPA

ENSG00000044090-CUL7

Ensembl

ENSP00000265348, ENST00000265348, ENSG00000044090, ENST00000690231, ENSP00000508461

PRO

Q14999

Pharos - Targets

Q14999

Orphanet

15826

PDB

7Z8B, 2JNG

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04637 TP53	20	Unfolded TP53 [cytosol] (R-HSA-6813797) TP53 [cytosol] (R-HSA-8869337) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) polySUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) TP53 F341C [nucleoplasm] (R-HSA-9726318) TP53 G334V [nucleoplasm] (R-HSA-9726126) TP53 L330H [nucleoplasm] (R-HSA-9726124) TP53 A347T [nucleoplasm] (R-HSA-9726339) TP53 R337C [nucleoplasm] (R-HSA-9726118) TP53 L344P [nucleoplasm] (R-HSA-9726075) TP53 L344R [nucleoplasm] (R-HSA-9726073) TP53 R337H [nucleoplasm] (R-HSA-9726169) TP53 R337P [nucleoplasm] (R-HSA-9726168) TP53 L330P [nucleoplasm] (R-HSA-9726136) TP53 L348S [nucleoplasm] (R-HSA-9726366) TP53 R337L [nucleoplasm] (R-HSA-9726163) TP53 K351E [nucleoplasm] (R-HSA-9726258) TP53 F338I [nucleoplasm] (R-HSA-9726358) TP53 R342P [nucleoplasm] (R-HSA-9726101) TP53 L330R [nucleoplasm] (R-HSA-9726133)	0.888	16
UniProt:O75147-2 OBSL1			0.544	4