Reactome | DECR1 [mitochondrial matrix]

DECR1 [mitochondrial matrix]

Stable Identifier

R-HSA-53523

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

2,4-dienoyl-CoA reductase, mitochondrial precursor , 2,4- dienoyl-CoA reductase (NADPH), 4-enoyl-CoA reductase (NADPH)

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q16698 DECR1

Gene Names

DECR1, DECR, SDR18C1

Chain

transit peptide:1-34, chain:35-335

Reference Genes

BioGPS Gene:1666 DECR1

COSMIC (genes):DECR1 DECR1

CTD Gene:1666 DECR1

dbSNP Gene:1666 DECR1

ENSEMBL:ENSG00000104325 DECR1

ENSEMBL_homo_sapiens_GENE:ENSG00000104325.7 DECR1

HGNC:2753 DECR1

KEGG Gene (Homo sapiens):1666 DECR1

Monarch:1666 DECR1

NCBI Gene:1666 DECR1

OMIM:222745 DECR1

UCSC:Q16698 DECR1

Reference Transcript

Other Identifiers

11717060_a_at

1666

17070665

202447_PM_at

202447_at

3106311

3106312

3106318

3106319

3106320

3106326

3106327

3106328

3106332

3106333

3106334

3106339

3106344

3106345

3106348

3106350

3106351

3106352

3106353

3106354

3106355

3106356

3106357

38104_at

8147228

81472_r_at

A_23_P71464

GE475973

GE54429

GO:0003824

GO:0005634

GO:0005654

GO:0005739

GO:0005759

GO:0005829

GO:0006629

GO:0006631

GO:0006635

GO:0008670

GO:0016491

GO:0042802

GO:0043226

GO:0070402

GO:0120162

GO:1902494

HMNXSV003015764

PH_hs_0024993

TC08000547.hg

U49352_at

g4503300_3p_at

Participates

as a component of

DECR1 tetramer [mitochondrial matrix] (Homo sapiens)

Inferred To

Homologues of DECR1 [mitochondrial matrix] (Caenorhabditis elegans)

DECR1 [mitochondrial matrix] (Bos taurus)

DECR1 [mitochondrial matrix] (Caenorhabditis elegans)

DECR1 [mitochondrial matrix] (Canis familiaris)

DECR1 [mitochondrial matrix] (Gallus gallus)

DECR1 [mitochondrial matrix] (Mus musculus)

DECR1 [mitochondrial matrix] (Rattus norvegicus)

DECR1 [mitochondrial matrix] (Sus scrofa)

decr1 [mitochondrial matrix] (Xenopus tropicalis)

Cross References

RefSeq

XP_016868636.1, XP_016868637.1, NP_001350.1, NP_001317504.1

OpenTargets

ENSG00000104325

GeneCards

Q16698

HPA

ENSG00000104325-DECR1

Ensembl

ENSP00000429779, ENST00000522161, ENSP00000220764, ENSG00000104325, ENST00000220764

PRO

Q16698

Pharos - Targets

Q16698

Orphanet

24462

HMDB Protein

HMDBP01040

PDB

1W73, 1W8D, 1W6U

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95997 PTTG1	2	K11polyUb-PTTG1 [cytosol] (R-HSA-3095943) PTTG1 [cytosol] (R-HSA-174190)	0.564	2

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