RNF43 R330fs*89 [plasma membrane]

Stable Identifier
R-HSA-5340581
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Icon
RNF43 R330fs*89 [plasma membrane] icon
RNF43 R330fs*89 [plasma membrane] icon
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
23847203 Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma

Lu, B, Liu, J, Woolfenden, S, Hsieh, MH, Smith, TR, Pan, S, Xie, Y, Bagdasarian, L, Charlat, O, Meyer, R, Ng, N, Bottiglio, C, McLaughlin, ME, Cong, F, Growney, JD, Jiang, X, Porter, JA, Avello, M, Hao, HX

Proc. Natl. Acad. Sci. U.S.A. 2013
External Reference Information
External Reference
UniProt:Q68DV7 RNF43
Gene Names
RNF43
Chain
signal peptide:1-23, chain:24-783
Reference Genes
BioGPS Gene:54894 RNF43
COSMIC (genes):RNF43 RNF43
CTD Gene:54894 RNF43
dbSNP Gene:54894 RNF43
ENSEMBL:ENSG00000108375 RNF43
HGNC:18505 RNF43
KEGG:hsa:54894 RNF43
Monarch:54894 RNF43
NCBI Gene:54894 RNF43
OMIM:612482 RNF43
UCSC:Q68DV7 RNF43
Reference Transcript
Other Identifiers
11720449_a_at
11720450_a_at
11750672_a_at
11756284_x_at
11758834_at
11760630_at
16847095
218704_PM_at
218704_at
3764400
3764401
3764402
3764406
3764407
3764408
3764409
3764410
3764411
3764412
3764413
3764414
3764415
3764416
3764418
3764419
3764431
3764435
3764436
3764437
3764438
3764439
3764440
3764441
3764442
45538_s_at
49316_at
54894
8016994
A_23_P3934
A_33_P3213029
GE82218
GO:0003824
GO:0004842
GO:0005109
GO:0005515
GO:0005634
GO:0005635
GO:0005783
GO:0005789
GO:0005886
GO:0006511
GO:0016020
GO:0016055
GO:0016567
GO:0016740
GO:0030178
GO:0038018
GO:0043226
GO:0046872
GO:0061630
GO:0072089
GO:0140096
HMNXSV003017390
ILMN_1700606
PH_hs_0031041
TC17001732.hg
g8923298_3p_at
Participates
as a member of
Other forms of this molecule
RNF43 [plasma membrane]
ub-RNF43 [plasma membrane]
RNF43 G659Vfs*41 [plasma membrane]
RNF43 F69C [plasma membrane]
RNF43 P154L [plasma membrane]
RNF43 R132* [plasma membrane]
RNF43 R117Afs*41 [plasma membrane]
RNF43 A169T [plasma membrane]
RNF43 E174* [plasma membrane]
Modified Residues
Name
Replacement of residues 330 to 417 by HLTKNQVEDSTSFASIPAMPTTTSLLPTCWALPGVQWLGPHDLVPSCHPRSQAWALGITASPELHIPGLQESSSAWQEPSTPMHKAGD
Disease
Name Identifier Synonyms
pancreatic cancer DOID:1793 malignant neoplasm of tail of pancreas, pancreatic tumor, Ca body of pancreas, pancreas neoplasm, malignant neoplasm of body of pancreas, pancreatic neoplasm, malignant tumor of body of pancreas (disorder), Ca tail of pancreas (disorder), malignant neoplasm of head of pancreas, Ca tail of pancreas, malignant tumor of tail of pancreas (disorder), neoplasm of pancreas (disorder), Ca head of pancreas, Ca body of pancreas (disorder)
Cross References
RefSeq
COSMIC
OpenTargets
ENSEMBL
HPA
PRO
Pharos - Targets
Orphanet
GlyGen
PDB
Interactors (3)
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