LRP5 del666-809

Stable Identifier
R-HSA-5339694
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
18044981 An LRP5 receptor with internal deletion in hyperparathyroid tumors with implications for deregulated WNT/beta-catenin signaling

Björklund, P, Akerström, G, Westin, G

PLoS Med. 2007
19158955 The internally truncated LRP5 receptor presents a therapeutic target in breast cancer

Björklund, P, Svedlund, J, Olsson, AK, Akerström, G, Westin, G

PLoS ONE 2009
External Reference Information
External Reference
Gene Names
LRP5, LR3, LRP7
Chain
signal peptide:1-31, chain:32-1615
Other Identifiers
0005700064
11727159_a_at
13001
16728066
209468_at
30505
3337517
3337518
3337539
3337548
3337549
3337550
3337561
3337565
3337574
3337576
3337578
3337579
3337581
3337582
3337588
3337589
3337590
3337592
3337595
3337598
3337599
3337600
3337606
3337609
3337610
3337611
3955653
3955654
4041
41831_at
7942007
A_23_P1505
AAC36467
AAC72791
AAI50596
AAK52433
AB017498
AF064548
AF077820
AF283320
AF283321
AP000807
BAA33051
BC150595
CAB013001
CCDS8181
CH471076
E9PHY1
EAW74705
ENSG00000162337
ENSP00000294304
ENST00000294304
EntrezGene:4041
g3582144_3p_at
GE54706
GO:0000278
GO:0001702
GO:0001944
GO:0002053
GO:0002076
GO:0002376
GO:0003013
GO:0003674
GO:0004871
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005783
GO:0005886
GO:0005975
GO:0006007
GO:0006464
GO:0006629
GO:0006810
GO:0006897
GO:0007049
GO:0007165
GO:0007267
GO:0007275
GO:0008150
GO:0008203
GO:0008217
GO:0008219
GO:0008283
GO:0008284
GO:0009056
GO:0009058
GO:0009314
GO:0009790
GO:0009952
GO:0016020
GO:0016021
GO:0016055
GO:0016192
GO:0017147
GO:0030154
GO:0032991
GO:0033690
GO:0034641
GO:0035019
GO:0035108
GO:0035426
GO:0040011
GO:0042074
GO:0042592
GO:0042632
GO:0042733
GO:0042813
GO:0042981
GO:0043226
GO:0043235
GO:0043434
GO:0044281
GO:0044332
GO:0045600
GO:0045668
GO:0045669
GO:0045840
GO:0045893
GO:0045944
GO:0046849
GO:0046850
GO:0048539
GO:0048856
GO:0048870
GO:0051091
GO:0060033
GO:0060042
GO:0060070
GO:0060348
GO:0060349
GO:0060444
GO:0060603
GO:0060612
GO:0060764
GO:0060828
GO:0061178
GO:0061299
GO:0061304
GO:0071901
GO:0071936
GO:0140014
GO:1902262
GO:1904928
GO:1990851
GO:1990909
HGNC:6697
HPA030505
ILMN_1702775
ILMN_2075892
IPR000033
IPR000742
IPR002172
IPR011042
IPR017049
IPR023415
IPR036055
LRP5
LRP5-201
MIM:133780
MIM:144750
MIM:166710
MIM:259770
MIM:601813
MIM:601884
MIM:603506
MIM:607634
MIM:607636
MIM:617875
NM_001291902
NM_002335
NP_001278831
NP_002326
PF00057
PF00058
PF14670
PH_hs_0000640
PR00261
SM00135
SM00181
SM00192
TC11000707.hg
uc001ont.4
UPI0000073246
XM_005273994
XM_011545029
XM_011545030
XM_011545031
XP_005274051
XP_011543331
XP_011543332
XP_011543333
XR_949925
XR_949926
Participant Of
Other forms of this molecule
Modified Residues
Name
Deletion of residues 666 to 809
Disease
Name Identifier Synonyms
breast cancer 1612 malignant tumor of the breast, mammary cancer, malignant neoplasm of breast, mammary tumor, primary breast cancer, breast cancer, Ca breast - NOS, breast tumor
parathyroid carcinoma 1540 malignant neoplasm of parathyroid gland, malignant neoplasm of the Parathyroid, parathyroid gland cancer, neoplasm of parathyroid gland, carcinoma of Parathyroid gland, Parathyroid gland neoplasm, malignant tumor of parathyroid gland (disorder), parathyroid neoplasm
Cross References
GeneCards
PRO
Orphanet
HMDB Protein
Interactors (3)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q9BQB4 SOST  1 0.564 2
 UniProt:Q8J025 APCD1      0.524 3
 UniProt:Q6IMN6 CAPR2      0.524 3