GPR37L binds prosaposin

Stable Identifier
R-HSA-5336184
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane, extracellular region
ReviewStatus
5/5
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GPR37L binds prosaposin
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GPR37L1 and GPR73 are almost exclusively expressed in the nervous system. They bind and are activated by the secreted neuroprotective and glioprotective factor prosaposin and a fragment of this named prosaptide.

Literature References
PubMed ID Title Journal Year
23690594 GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin

Hall, RA, Meyer, RC, Schaefer, SA, Giddens, MM

Proc. Natl. Acad. Sci. U.S.A. 2013
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Orthologous Events
GPR37L binds prosaposin (Bos taurus)
GPR37L binds prosaposin (Canis familiaris)
GPR37L binds prosaposin (Danio rerio)
GPR37L binds prosaposin (Gallus gallus)
GPR37L binds prosaposin (Mus musculus)
GPR37L binds prosaposin (Rattus norvegicus)
GPR37L binds prosaposin (Sus scrofa)
GPR37L binds prosaposin (Xenopus tropicalis)
Authored
Jupe, S  (2014-02-28)
Reviewed
Jassal, B  (2014-01-24)
Created
Jupe, S  (2014-02-28)
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