Reactome | SCO1 [mitochondrial inner membrane]

SCO1 [mitochondrial inner membrane]

Stable Identifier

R-HSA-5336170

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Protein SCO1 homolog, mitochondrial, SCO1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O75880 SCO1

Gene Names

SCO1, SCOD1

Chain

transit peptide:1-67, chain:68-301

Reference Genes

BioGPS Gene:6341 SCO1

COSMIC (genes):SCO1 SCO1

CTD Gene:6341 SCO1

dbSNP Gene:6341 SCO1

ENSEMBL:ENSG00000133028 SCO1

HGNC:10603 SCO1

KEGG:hsa:6341 SCO1

Monarch:6341 SCO1

NCBI Gene:6341 SCO1

OMIM:603644 SCO1

UCSC:O75880 SCO1

Reference Transcript

Other Identifiers

11728242_a_at

16841425

223221_PM_at

223221_at

3745492

3745494

3745495

3745496

3745498

3745500

3745501

3745502

3745503

3745505

3745506

3745507

3745508

3745511

3745512

3745513

3745514

3745516

3745520

3745521

3745522

3745524

55225_at

63237_at

6341

65440_at

8012823

85831_r_at

A_23_P15466

GE54210

GO:0005507

GO:0005515

GO:0005739

GO:0005743

GO:0006878

GO:0008535

GO:0016531

GO:0030016

GO:0033617

GO:0043226

GO:0046872

GO:0065003

GO:0140104

HMNXSV003011990

ILMN_1728975

PH_hs_0001375

PH_hs_0009448

TC17001136.hg

g9963786_3p_at

Participates

as a component of

metallochaperone complex [mitochondrial inner membrane] (Homo sapiens)

Inferred To

Ghost homologue of SCO1 [mitochondrial inner membrane] (Danio rerio)

SCO1 [mitochondrial inner membrane] (Bos taurus)

SCO1 [mitochondrial inner membrane] (Caenorhabditis elegans)

SCO1 [mitochondrial inner membrane] (Canis familiaris)

SCO1 [mitochondrial inner membrane] (Drosophila melanogaster)

SCO1 [mitochondrial inner membrane] (Gallus gallus)

SCO1 [mitochondrial inner membrane] (Mus musculus)

SCO1 [mitochondrial inner membrane] (Rattus norvegicus)

SCO1 [mitochondrial inner membrane] (Sus scrofa)

Cross References

ENSEMBL

ENST00000255390, ENSP00000255390, ENSG00000133028

OpenTargets

ENSG00000133028

GeneCards

SCO1

HPA

ENSG00000133028-SCO1

PRO

O75880

Pharos - Targets

O75880

Orphanet

SCO1

HMDB Protein

HMDBP08256

PDB

2GVP, 1WP0, 2GT6, 2GT5, 2HRF, 2GGT, 2HRN, 2GQK, 2GQM, 2GQL

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14061 COX17	2	4xHC-COX17 [mitochondrial intermembrane space] (R-HSA-1307785) COX17 [mitochondrial intermembrane space] (R-HSA-1307788)	0.66	3
UniProt:Q8NEZ3 WDR19	2	WDR19 [ciliary tip] (R-HSA-5625347) WDR19 [cilium] (R-HSA-5610446)	0.508	2
UniProt:O75489 NDUFS3	2	NDUFS3 [mitochondrial matrix] (R-HSA-163927) NDUFS3 [cytosol] (R-HSA-9714751)	0.483	3