Reactome | COX7A2 [mitochondrial inner membrane]

COX7A2 [mitochondrial inner membrane]

Stable Identifier

R-HSA-5336134

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Cytochrome c oxidase subunit 7A2, mitochondrial, CX7A2_HUMAN

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional Regulation by TP53 (Homo sapiens)
      - TP53 Regulates Metabolic Genes (Homo sapiens)
        
        Electron transfer from reduced cytochrome c to molecular oxygen (Homo sapiens)
        
        Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
        
        COX7A1,2,2L [mitochondrial inner membrane] (Homo sapiens)
        
        COX7A2 [mitochondrial inner membrane] (Homo sapiens)
        
        Cytochrome c oxidase:CO [mitochondrial inner membrane] (Homo sapiens)
        
        Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
        
        COX7A1,2,2L [mitochondrial inner membrane] (Homo sapiens)
        
        COX7A2 [mitochondrial inner membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P14406 COX7A2

Gene Names

COX7A2, COX7AL

Chain

transit peptide:1-23, chain:24-83

Reference Genes

BioGPS Gene:1347 COX7A2

COSMIC (genes):COX7A2 COX7A2

CTD Gene:1347 COX7A2

dbSNP Gene:1347 COX7A2

ENSEMBL:ENSG00000112695 COX7A2

HGNC:2288 COX7A2

KEGG:hsa:1347 COX7A2

Monarch:1347 COX7A2

NCBI Gene:1347 COX7A2

OMIM:123996 COX7A2

UCSC:P14406 COX7A2

Reference Transcript

RefSeq:NM_001865.3 COX7A2

Other Identifiers

11721466_s_at

11753849_a_at

11753850_x_at

11753892_x_at

11758845_at

1347

17020918

201597_PM_at

201597_at

2736751

2961301

2961302

2961303

2961305

2961306

2961307

2961308

2961309

2961310

2961312

2961313

2961314

2961316

41760_at

8127629

A_23_P81690

GE61597

GE79049

GO:0002082

GO:0003824

GO:0005515

GO:0005739

GO:0005743

GO:0005746

GO:0005751

GO:0006091

GO:0006119

GO:0006123

GO:0007005

GO:0016020

GO:0016491

GO:0031966

GO:0043226

GO:0045333

GO:0065003

GO:0097250

GO:0098803

HMNXSV003001473

ILMN_1701293

ILMN_1887013

PH_hs_0004116

TC06001880.hg

TC06003719.hg

X15822_at

g4502988_3p_s_at

g4502988_3p_x_at

Participates

as a member of

COX7A1,2,2L [mitochondrial inner membrane] (Homo sapiens)

Inferred To

cox7a2 [mitochondrial inner membrane] (Xenopus tropicalis)

cox7a2a [mitochondrial inner membrane] (Danio rerio)

COX7A2 [mitochondrial inner membrane] (Bos taurus)

COX7A2 [mitochondrial inner membrane] (Gallus gallus)

COX7A2 [mitochondrial inner membrane] (Sus scrofa)

COX7A [mitochondrial inner membrane] (Drosophila melanogaster)

LOC119863903 [mitochondrial inner membrane] (Canis familiaris)

Cox7a2 [mitochondrial inner membrane] (Mus musculus)

Cox7a2 [mitochondrial inner membrane] (Rattus norvegicus)

Cross References

ENSEMBL

ENSP00000506727, ENSG00000112695, ENST00000684430

OpenTargets

ENSG00000112695

GeneCards

COX7A2

HPA

ENSG00000112695-COX7A2

PRO

P14406

Pharos - Targets

P14406

GlyGen

P14406

HMDB Protein

HMDBP03042

PDB

5Z62

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P00403 MT-CO2	2	nascent MT-CO2 [mitochondrial matrix] (R-HSA-9902095) nascent MT-CO2 [mitochondrial inner membrane] (R-HSA-164302)	0.564	3