HSF1:HSP90:HDAC6:VCP:PTGES3

Stable Identifier
R-HSA-5324677
Type
Complex
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
16403413 The co-chaperone p23 arrests the Hsp90 ATPase cycle to trap client proteins

McLaughlin, SH, Sobott, F, Yao, ZP, Zhang, W, Nielsen, PR, Grossmann, JG, Laue, ED, Robinson, CV, Jackson, SE

J. Mol. Biol. 2006
17785525 HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates

Boyault, C, Zhang, Y, Fritah, S, Caron, C, Gilquin, B, Kwon, SH, Garrido, C, Yao, TP, Vourc'h, C, Matthias, P, Khochbin, S

Genes Dev. 2007
9727490 Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1

Zou, J, Guo, Y, Guettouche, T, Smith, DF, Voellmy, R

Cell 1998
11583998 Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex

Guo, Y, Guettouche, T, Fenna, M, Boellmann, F, Pratt, WB, Toft, DO, Smith, DF, Voellmy, R

J. Biol. Chem. 2001
21183720 N-terminal domain of human Hsp90 triggers binding to the cochaperone p23

Karagöz, GE, Duarte, AM, Ippel, H, Uetrecht, C, Sinnige, T, van Rosmalen, M, Hausmann, J, Heck, AJ, Boelens, R, Rüdiger, SG

Proc. Natl. Acad. Sci. U.S.A. 2011
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