Reactome | CYP1A2 [endoplasmic reticulum membrane]

CYP1A2 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-52625

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

CYPIA2, Cytochrome P450 1A2 , P450-P3, P(3)450, P450 4

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P05177 CYP1A2

Gene Names

CYP1A2

Chain

initiator methionine:, chain:2-516

Reference Genes

BioGPS Gene:1544 CYP1A2

COSMIC (genes):CYP1A2 CYP1A2

CTD Gene:1544 CYP1A2

dbSNP Gene:1544 CYP1A2

ENSEMBL:ENSG00000140505 CYP1A2

HGNC:2596 CYP1A2

KEGG:hsa:1544 CYP1A2

Monarch:1544 CYP1A2

NCBI Gene:1544 CYP1A2

OMIM:108330 CYP1A2

UCSC:P05177 CYP1A2

Reference Transcript

RefSeq:NM_000761.4 CYP1A2

Other Identifiers

1080_s_at

11732107_a_at

11732108_x_at

1544

16803050

207608_3p_x_at

207608_PM_x_at

207608_x_at

207609_PM_s_at

207609_s_at

3601830

3601831

3601832

3601833

3601834

3601835

3601838

3601839

3633087

7984862

A_23_P206113

A_33_P3253747

GE57967

GO:0003824

GO:0004497

GO:0005506

GO:0005515

GO:0005783

GO:0005789

GO:0006091

GO:0006629

GO:0006631

GO:0006706

GO:0006778

GO:0006805

GO:0008202

GO:0008203

GO:0008210

GO:0008395

GO:0009055

GO:0009403

GO:0009404

GO:0009791

GO:0009820

GO:0010468

GO:0016020

GO:0016098

GO:0016491

GO:0016705

GO:0016712

GO:0016829

GO:0018894

GO:0019369

GO:0019373

GO:0019899

GO:0020037

GO:0030324

GO:0032259

GO:0032451

GO:0032787

GO:0034875

GO:0042178

GO:0042445

GO:0042572

GO:0042759

GO:0043226

GO:0043231

GO:0045333

GO:0046222

GO:0046872

GO:0048856

GO:0050665

GO:0070330

GO:0070989

GO:0071276

GO:0097267

GO:0101020

GO:0101021

GO:0106256

HMNXSV003031691

ILMN_1683607

M31667_f_at

TC15000684.hg

g13325061_3p_a_at

g6470136_3p_a_at

Participates

as a member of

Inferred To

CYP1A2 [endoplasmic reticulum membrane] (Bos taurus)

CYP1A2 [endoplasmic reticulum membrane] (Danio rerio)

CYP1A2 [endoplasmic reticulum membrane] (Gallus gallus)

CYP1A2 [endoplasmic reticulum membrane] (Mus musculus)

CYP1A2 [endoplasmic reticulum membrane] (Rattus norvegicus)

CYP1A2 [endoplasmic reticulum membrane] (Sus scrofa)

Cross References

ZINC - World Drugs

CP1A2_HUMAN

Guide to Pharmacology - Targets

1319

ENSEMBL

ENSP00000342007, ENST00000343932

OpenTargets

ENSG00000140505

ZINC - FDA approved

CP1A2_HUMAN

ZINC - Substances

CP1A2_HUMAN

ZINC - Biogenic

CP1A2_HUMAN

ZINC target

P05177

PRO

P05177

GlyGen

P05177

PDB

2HI4

ZINC - Investigational

CP1A2_HUMAN

ZINC - Metabolites

CP1A2_HUMAN

HPA

ENSG00000140505-CYP1A2

Pharos - Targets

P05177

ZINC - Predictions - Purchasable

CP1A2_HUMAN

HMDB Protein

HMDBP01560

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95870 ABHGA			0.556	3
UniProt:O00264 PGRMC1	2	PGRMC1 [plasma membrane] (R-HSA-6806314) PGRMC1 [specific granule membrane] (R-HSA-6799648)	0.527	3
UniProt:P54764 EPHA4	2	p-Y596,Y602-EPHA4 [plasma membrane] (R-HSA-3928352) EPHA4 [plasma membrane] (R-HSA-2682325)	0.527	2