Reactome | DNAJB6 [cytosol]

DNAJB6 [cytosol]

Stable Identifier

R-HSA-5252014

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

DnaJ homolog subfamily B member 6, DNJB6_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O75190 DNAJB6

Gene Names

DNAJB6, HSJ2, MRJ, MSJ1

Chain

initiator methionine:, chain:2-326

Reference Genes

BioGPS Gene:10049 DNAJB6

COSMIC (genes):DNAJB6 DNAJB6

CTD Gene:10049 DNAJB6

dbSNP Gene:10049 DNAJB6

ENSEMBL:ENSG00000105993 DNAJB6

HGNC:14888 DNAJB6

KEGG:hsa:10049 DNAJB6

Monarch:10049 DNAJB6

NCBI Gene:10049 DNAJB6

OMIM:611332 DNAJB6

UCSC:O75190 DNAJB6

Reference Transcript

Participates

as a member of

DNAJB1,B6,C2,C7 [cytosol] (Homo sapiens)

Other forms of this molecule

DNAJB6 [nucleoplasm]

Inferred To

dnajb6a [cytosol] (Danio rerio)

dnj-24 [cytosol] (Caenorhabditis elegans)

Dnajb6 [cytosol] (Mus musculus)

Dnajb6 [cytosol] (Rattus norvegicus)

DNAJB6 [cytosol] (Canis familiaris)

DNAJB6 [cytosol] (Plasmodium falciparum)

DNAJB6 [cytosol] (Schizosaccharomyces pombe)

DNAJB6 [cytosol] (Sus scrofa)

Cross References

ENSEMBL

ENST00000262177, ENSP00000262177, ENSP00000397556, ENSG00000105993, ENST00000429029

OpenTargets

ENSG00000105993

GeneCards

DNAJB6

HPA

ENSG00000105993-DNAJB6

PRO

O75190

Pharos - Targets

O75190

Orphanet

DNAJB6

PDB

7JSQ, 7QBY, 6U3S, 6U3R

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13123 IK	1	IK [nucleoplasm] (R-HSA-9770239)	0.556	3
UniProt:P31948 STIP1	1	STIP1 [cytosol] (R-HSA-443857)	0.527	2
UniProt:Q9UNE7 STUB1	1	STUB1 [cytosol] (R-HSA-975970)	0.527	2
UniProt:Q9Y468 L3MBTL1	1	L3MBTL1 [nucleoplasm] (R-HSA-3222110)	0.527	2
UniProt:Q13451 FKBP5	2	FKBP5 [nucleoplasm] (R-HSA-8939165) FKBP5 [cytosol] (R-HSA-5618096)	0.527	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	10
UniProt:P11142 HSPA8	10	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [secretory granule lumen] (R-HSA-6801530) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.482	2
UniProt:O75923 DYSF	1	DYSF [cytoplasmic vesicle membrane] (R-HSA-5263626)	0.454	2

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