Hikeshi binds HSP70s:ATP

Stable Identifier
R-HSA-5251942
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Hikeshi (C11orf73) binds ATP-bound heat-shock 70 proteins in the cytosol - leave here
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Hikeshi binds HSP70s:ATP
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Protein Hikeshi (C11orf73) is a nuclear import carrier protein for heat-shock 70 proteins (HSP70s) in response to heat-shock stress. C11orf73 binds HSP70s in the cytosol, ready for nuclear import (Kose et al. 2012).

Literature References
PubMed ID Title Journal Year
22541429 Hikeshi, a nuclear import carrier for Hsp70s, protects cells from heat shock-induced nuclear damage

Imamoto, N, Furuta, M, Kose, S

Cell 2012
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Orthologous Events
Hikeshi binds HSP70s:ATP (Bos taurus)
Hikeshi binds HSP70s:ATP (Caenorhabditis elegans)
Hikeshi binds HSP70s:ATP (Canis familiaris)
Hikeshi binds HSP70s:ATP (Danio rerio)
Hikeshi binds HSP70s:ATP (Drosophila melanogaster)
Hikeshi binds HSP70s:ATP (Mus musculus)
Hikeshi binds HSP70s:ATP (Rattus norvegicus)
Hikeshi binds HSP70s:ATP (Sus scrofa)
Hikeshi binds HSP70s:ATP (Xenopus tropicalis)
Authored
Jassal, B  (2014-02-05)
Reviewed
D'Eustachio, P  (2015-02-11)
Created
Jassal, B  (2014-02-05)
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