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CNGA1 [plasma membrane]
Stable Identifier
R-HSA-52425
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
cGMP-gated cation channel alpha 1, CNG channel alpha 1, CNG-1, CNG1, Cyclic nucleotide gated channel alpha 1, Cyclic nucleotide gated channel, photoreceptor, Cyclic-nucleotide-gated cation channel 1, Rod photoreceptor cGMP-gated channel alpha subunit
Icon
Locations in the PathwayBrowser
Expand all
Sensory Perception (Homo sapiens)
Visual phototransduction (Homo sapiens)
The phototransduction cascade (Homo sapiens)
Activation of the phototransduction cascade (Homo sapiens)
cGMP dissociates from CNG channels (Homo sapiens)
CNG channel [plasma membrane] (Homo sapiens)
CNGA1 [plasma membrane] (Homo sapiens)
cGMP:CNG channel [plasma membrane] (Homo sapiens)
CNG channel [plasma membrane] (Homo sapiens)
CNGA1 [plasma membrane] (Homo sapiens)
cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Homo sapiens)
cGMP:CNG channel [plasma membrane] (Homo sapiens)
CNG channel [plasma membrane] (Homo sapiens)
CNGA1 [plasma membrane] (Homo sapiens)
Inactivation, recovery and regulation of the phototransduction cascade (Homo sapiens)
CALM1:Ca2+ binds CNG channel (Homo sapiens)
CALM1:Ca2+:CNG channel [plasma membrane] (Homo sapiens)
CNG channel [plasma membrane] (Homo sapiens)
CNGA1 [plasma membrane] (Homo sapiens)
CNG channel [plasma membrane] (Homo sapiens)
CNGA1 [plasma membrane] (Homo sapiens)
cGMP binds CNG channel to form cGMP:CNG channel (Homo sapiens)
CNG channel [plasma membrane] (Homo sapiens)
CNGA1 [plasma membrane] (Homo sapiens)
cGMP:CNG channel [plasma membrane] (Homo sapiens)
CNG channel [plasma membrane] (Homo sapiens)
CNGA1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P29973 CNGA1
Gene Names
CNGA1, CNCG, CNCG1
Chain
chain:1-686
Reference Genes
BioGPS Gene:1259 CNGA1
COSMIC (genes):CNGA1 CNGA1
CTD Gene:1259 CNGA1
dbSNP Gene:1259 CNGA1
ENSEMBL:ENSG00000198515 CNGA1
HGNC:2148 CNGA1
Monarch:1259 CNGA1
NCBI Gene:1259 CNGA1
OMIM:123825 CNGA1
UCSC:P29973 CNGA1
Reference Transcript
RefSeq:XM_017007712.1 CNGA1
RefSeq:NM_001142564.1 CNGA1
RefSeq:NM_000087.3 CNGA1
RefSeq:XM_011513623.2 CNGA1
Other Identifiers
11730071_a_at
11740815_a_at
11758533_s_at
1259
16975737
206417_PM_at
206417_at
2768324
2768325
2768326
2768327
2768328
2768329
2768330
2768331
2768332
2768333
2768334
2768336
2768338
2768348
2768351
37840_at
8100202
A_23_P92536
A_24_P256722
GE58775
GO:0001750
GO:0005215
GO:0005216
GO:0005222
GO:0005223
GO:0005262
GO:0005272
GO:0005515
GO:0005886
GO:0006811
GO:0006814
GO:0006816
GO:0007601
GO:0016020
GO:0017071
GO:0030552
GO:0030553
GO:0035725
GO:0042622
GO:0044877
GO:0050877
GO:0055085
GO:0070588
GO:0098655
GO:0120200
HMNXSV003013044
ILMN_1786353
PH_hs_0030868
S42457_at
TC04001172.hg
TC04002539.hg
g4502914_3p_at
Participates
as a component of
CNG channel [plasma membrane] (Homo sapiens)
Inferred To
cng-2 [plasma membrane]
(Caenorhabditis elegans)
Homologues of CNGA1 [plasma membrane]
(Caenorhabditis elegans)
Homologues of CNGA1 [plasma membrane]
(Drosophila melanogaster)
CNGA1 [plasma membrane]
(Bos taurus)
CNGA1 [plasma membrane]
(Caenorhabditis elegans)
CNGA1 [plasma membrane]
(Canis familiaris)
CNGA1 [plasma membrane]
(Drosophila melanogaster)
CNGA1 [plasma membrane]
(Gallus gallus)
CNGA1 [plasma membrane]
(Mus musculus)
CNGA1 [plasma membrane]
(Rattus norvegicus)
CNGA1 [plasma membrane]
(Sus scrofa)
Dmel\CG42260 [plasma membrane]
(Drosophila melanogaster)
cng-1 [plasma membrane]
(Caenorhabditis elegans)
cng-3 [plasma membrane]
(Caenorhabditis elegans)
che-6 [plasma membrane]
(Caenorhabditis elegans)
Cross References
Guide to Pharmacology - Targets
394
ENSEMBL
ENST00000402813
,
ENSP00000389881
,
ENST00000514170
,
ENSP00000384264
,
ENST00000420489
,
ENSP00000426862
OpenTargets
ENSG00000198515
ZINC - Substances
CNGA1_HUMAN
ZINC target
P29973
PRO
P29973
GlyGen
P29973
PDB
7RHL
,
7LG1
,
7RHI
,
7RH9
,
7LFX
,
7RHK
,
7LFW
,
7LFT
,
7RHH
,
7RHG
,
7LFY
,
7RHJ
HPA
ENSG00000198515-CNGA1
Pharos - Targets
P29973
Orphanet
CNGA1
ZINC - Predictions - Purchasable
CNGA1_HUMAN
HMDB Protein
HMDBP01124
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