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MeR12-HIST2H2AC [nucleoplasm]
Stable Identifier
R-HSA-5229227
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
HIST2H2AC, Histone H2A.q
Locations in the PathwayBrowser
Expand all
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
RMTs methylate histone arginines (Homo sapiens)
PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Homo sapiens)
Me2aR12-histone H2A, MeR12-histone H2A [nucleoplasm] (Homo sapiens)
MeR12-histone H2A [nucleoplasm] (Homo sapiens)
MeR12-histone HIST2H2A [nucleoplasm] (Homo sapiens)
MeR12-HIST2H2AC [nucleoplasm] (Homo sapiens)
MeR12-histone H2A, Histone H2A [nucleoplasm] (Homo sapiens)
MeR12-histone H2A [nucleoplasm] (Homo sapiens)
MeR12-histone HIST2H2A [nucleoplasm] (Homo sapiens)
MeR12-HIST2H2AC [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q16777 H2AC20
Gene Names
H2AC20, H2AFQ, HIST2H2AC
Chain
initiator methionine:, chain:2-129
Reference Genes
BioGPS Gene:8338 H2AC20
CTD Gene:8338 H2AC20
dbSNP Gene:8338 H2AC20
ENSEMBL:ENSG00000184260 HIST2H2AC
ENSEMBL_homo_sapiens_GENE:ENSG00000184260.6 H2AC20
HGNC:4738 H2AC20
KEGG Gene (Homo sapiens):8338 H2AC20
Monarch:8338 H2AC20
NCBI Gene:8338 H2AC20
OMIM:602797 H2AC20
UCSC:Q16777 H2AC20
Reference Transcript
RefSeq:NM_003517.2 H2AC20
Other Identifiers
11715204_x_at
11759258_at
16670401
2357932
2357953
2357954
2357955
2357956
2357957
2357958
2357960
2434088
7905088
8338
ADDON002791.hg
A_14_P101364
A_23_P301247
A_24_P8721
GO:0000786
GO:0003674
GO:0003677
GO:0005198
GO:0005576
GO:0005615
GO:0005634
GO:0005694
GO:0008150
GO:0030527
GO:0043226
GO:0043229
GO:0046982
GO:0070062
HMNXSV003057187
ILMN_1768973
PH_hs_0030080
PH_hs_0033186
TC01006326.hg
Participates
as a member of
MeR12-histone HIST2H2A [nucleoplasm] (Homo sapiens)
Other forms of this molecule
K63polyUb-HIST2H2AC [nucleoplasm]
Ub-HIST2H2AC [nucleoplasm]
AcK6-HIST2H2AC [nucleoplasm]
Me2aR30-HIST2H2AC [nucleoplasm]
MeR30-HIST2H2AC [nucleoplasm]
Me2aR4-HIST2H2AC [nucleoplasm]
HIST2H2AC [nucleoplasm]
AcK-HIST2H2AC [nucleoplasm]
HIST2H2AC [extracellular region]
Me2aR12-HIST2H2AC [nucleoplasm]
Me2sR4-HIST2H2AC [nucleoplasm]
MeR4-HIST2H2AC [nucleoplasm]
Inferred To
LOC100485548 [nucleoplasm]
(Xenopus tropicalis)
LOC100487632 [nucleoplasm]
(Xenopus tropicalis)
LOC116411633 [nucleoplasm]
(Xenopus tropicalis)
H2ac18 [nucleoplasm]
(Rattus norvegicus)
his-35 [nucleoplasm]
(Caenorhabditis elegans)
MeR12-HIST2H2AC [nucleoplasm]
(Bos taurus)
MeR12-HIST2H2AC [nucleoplasm]
(Canis familiaris)
MeR12-HIST2H2AC [nucleoplasm]
(Plasmodium falciparum)
H2AC18 [nucleoplasm]
(Bos taurus)
HTA1 [nucleoplasm]
(Saccharomyces cerevisiae)
HTA2 [nucleoplasm]
(Saccharomyces cerevisiae)
H2Av2 [nucleoplasm]
(Dictyostelium discoideum)
His2A:CG33862 [nucleoplasm]
(Drosophila melanogaster)
hta1 [nucleoplasm]
(Schizosaccharomyces pombe)
H2AC20 [nucleoplasm]
(Sus scrofa)
his-65 [nucleoplasm]
(Caenorhabditis elegans)
hta2 [nucleoplasm]
(Schizosaccharomyces pombe)
h2ac16 [nucleoplasm]
(Xenopus tropicalis)
H2ac20 [nucleoplasm]
(Mus musculus)
LOC116407737 [nucleoplasm]
(Xenopus tropicalis)
LOC100487067 [nucleoplasm]
(Xenopus tropicalis)
h2ax1 [nucleoplasm]
(Danio rerio)
zgc:56685 [nucleoplasm]
(Danio rerio)
H2A-IX [nucleoplasm]
(Gallus gallus)
H2AX [nucleoplasm]
(Dictyostelium discoideum)
H2Av3 [nucleoplasm]
(Dictyostelium discoideum)
htas-1 [nucleoplasm]
(Caenorhabditis elegans)
H2Av1 [nucleoplasm]
(Dictyostelium discoideum)
Homologues of MeR12-HIST2H2AC [nucleoplasm]
(Bos taurus)
Homologues of MeR12-HIST2H2AC [nucleoplasm]
(Caenorhabditis elegans)
Homologues of MeR12-HIST2H2AC [nucleoplasm]
(Danio rerio)
Homologues of MeR12-HIST2H2AC [nucleoplasm]
(Dictyostelium discoideum)
Homologues of MeR12-HIST2H2AC [nucleoplasm]
(Drosophila melanogaster)
Homologues of MeR12-HIST2H2AC [nucleoplasm]
(Saccharomyces cerevisiae)
Homologues of MeR12-HIST2H2AC [nucleoplasm]
(Schizosaccharomyces pombe)
Homologues of MeR12-HIST2H2AC [nucleoplasm]
(Xenopus tropicalis)
LOC101732059 [nucleoplasm]
(Xenopus tropicalis)
His2A:CG33859 [nucleoplasm]
(Drosophila melanogaster)
Modified Residues
Name
omega-N-methyl-L-arginine at 12
Coordinate
12
PsiMod Name
omega-N-methyl-L-arginine
PsiMod Definition
A protein modification that effectively converts an L-arginine residue to N(omega)-methyl-L-arginine.
Cross References
RefSeq
NP_003508.1
OpenTargets
ENSG00000184260
HPA
ENSG00000184260-H2AC20
GeneCards
Q16777
Ensembl
ENST00000331380
,
ENSG00000184260
,
ENSP00000332194
PRO
Q16777
Pharos - Targets
Q16777
HMDB Protein
HMDBP01943
PDB
8SYP
,
8EVI
,
8EVJ
,
7U0J
,
7U0I
,
6Y5E
,
8EVG
,
8SPS
,
7U0G
,
8EVH
,
8DK5
,
8SPU
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q08945 SSRP1
1
SSRP1 [nucleoplasm]
(R-HSA-65105)
0.527
2
UniProt:P08253 MMP2
5
MMP2(67-109) [extracellular region]
(R-HSA-1604371)
MMP2(67-660) [extracellular region]
(R-HSA-1604345)
MMP2(30-66) [extracellular region]
(R-HSA-1604347)
MMP2(30-660) [extracellular region]
(R-HSA-1604364)
MMP2(110-660) [extracellular region]
(R-HSA-381456)
0.527
2
UniProt:Q9H9Z2 LIN28A
1
LIN28A [cytosol]
(R-HSA-500391)
0.527
3
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