Clathrin-mediated endocytosis of TeNT HC:LC:gangliosides

Stable Identifier
R-HSA-5228411
Type
Reaction [omitted]
Species
Homo sapiens
Related Species
Clostridium tetani
Compartment
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Ganglioside-bound tetanus toxin disulfide-bonded heavy chain - light chain dimer (TeNT HC:LC) is taken up into the target cell by clathrin-mediated endocytosis (Deinhardt et al. 2006).

Literature References
PubMed ID Title Journal Year
16880274 Tetanus toxin is internalized by a sequential clathrin-dependent mechanism initiated within lipid microdomains and independent of epsin1

Deinhardt, K, Berninghausen, O, Willison, HJ, Hopkins, CR, Schiavo, G

J. Cell Biol. 2006
Participants
Participant Of
Disease
Name Identifier Synonyms
tetanus 11338 clostridial tetanus, Tetanus (disorder), Infection due to Clostridium tetani (disorder)
Authored
Reviewed
Created
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