p-T357,S358-MLKL [cytosol]

Stable Identifier
R-HSA-5218903
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q8NB16 MLKL
Gene Names
MLKL
Chain
chain:1-471
Reference Genes
BioGPS Gene:197259 MLKL
COSMIC (genes):MLKL MLKL
CTD Gene:197259 MLKL
dbSNP Gene:197259 MLKL
ENSEMBL:ENSG00000168404 MLKL
ENSEMBL_homo_sapiens_GENE:ENSG00000168404 MLKL
HGNC:26617 MLKL
KEGG Gene (Homo sapiens):197259 MLKL
Monarch:197259 MLKL
NCBI Gene:197259 MLKL
OMIM:615153 MLKL
UCSC:Q8NB16 MLKL
Reference Transcript
Other Identifiers
11754630_a_at
16828344
197259
238025_at
2MSV
3699083
3699086
3699087
3699090
3699091
3699093
3699104
3699105
3699107
3699108
3699110
3699111
3699114
3699119
3699120
3699121
3699125
3699126
3699127
3699128
3699129
4M67
4MWI
50829_at
5KNJ
5KO1
8002778
A_23_P61050
A_24_P185044
AAH28141
AC109599
AK091708
BAC03728
BC028141
CCDS32487
CCDS45528
ENSG00000168404
ENSP00000303118
ENSP00000308351
ENST00000306247
ENST00000308807
EntrezGene:197259
GE87884
GO:0000165
GO:0000166
GO:0003674
GO:0004674
GO:0004706
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005829
GO:0005886
GO:0006464
GO:0006468
GO:0006950
GO:0007165
GO:0007166
GO:0007256
GO:0007257
GO:0008150
GO:0008219
GO:0012501
GO:0016020
GO:0016301
GO:0019899
GO:0019901
GO:0022607
GO:0043167
GO:0044877
GO:0065003
GO:0070207
GO:0070266
HGNC:26617
Hs.119878.0.A1_3p_at
I3L2T9
I3L4Z5
ILMN_1667825
ILMN_1715863
ILMN_1737498
IPR000719
IPR001245
IPR011009
IPR036537
MIM:615153
MLKL
MLKL-201
MLKL-202
NM_001142497
NM_152649
NP_001135969
NP_689862
PF07714
TC16001270.hg
uc002fdb.3
uc002fdc.3
UPI000004073C
UPI0000071EE1
XM_005255834
XP_005255891
XR_001751858
XR_001751859
XR_001751860
XR_001751861
XR_001751862
XR_001751863
XR_429715
Participant Of
repeatedUnit
hasComponent
Other forms of this molecule
MLKL [cytosol]
Inferred To
Homologues of p-T357,S358-MLKL [cytosol] (Sus scrofa)
phospho-p-T357,S358-MLKL [cytosol] (Bos taurus)
phospho-p-T357,S358-MLKL [cytosol] (Mus musculus)
phospho-p-T357,S358-MLKL [cytosol] (Rattus norvegicus)
phospho-p-T357,S358-MLKL [cytosol] (Sus scrofa)
phospho-p-T357,S358-MLKL [cytosol] (Xenopus tropicalis)
Modified Residues
Name
O-phospho-L-serine at 358
Coordinate
358
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 357
Coordinate
357
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
OpenTargets
GeneCards
DOCK Blaster
PRO
HMDB Protein
PDB
Interactors (2)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q9Y572 RIPK3  2 0.641 10
 ChEBI:63770 NECROSULFONAMIDE      0.591 4