Reactome | MLKL [cytosol]

Stable Identifier

R-HSA-5218901

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

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Locations in the PathwayBrowser for interactor UniProt:Q9Y572 RIPK3

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External Reference Information

External Reference

UniProt:Q8NB16 MLKL

Gene Names

MLKL

Chain

chain:1-471

Reference Genes

COSMIC (genes):MLKL MLKL

ENSEMBL:ENSG00000168404 MLKL

Participates

as a component of

as an input of

Other forms of this molecule

p-T357,S358-MLKL [cytosol]

Inferred To

MLKL [cytosol] (Bos taurus)

MLKL [cytosol] (Dictyostelium discoideum)

MLKL [cytosol] (Gallus gallus)

MLKL [cytosol] (Mus musculus)

MLKL [cytosol] (Sus scrofa)

mlkl [cytosol] (Xenopus tropicalis)

Mlkl [cytosol] (Rattus norvegicus)

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y572 RIPK3	8	RIPK3 [cytosol] (R-HSA-450328) p-S199,227-RIPK3 [cytosol] (R-HSA-5218873) Ub-K55,363-RIPK3 [cytosol] (R-HSA-9688825) RIPK3(1-328) [cytosol] (R-HSA-9686917) RIPK3(329-518) [cytosol] (R-HSA-9686937) OGlcNAc-T467-RIPK3 [cytosol] (R-HSA-9687819) K33polyUb-K197,302,364-RIPK3 [cytosol] (R-HSA-9794180) p-S199,227, K48pUb-363-RIPK3 [cytosol] (R-HSA-9686933)	0.641	10
ChEBI:63770 NECROSULFONAMIDE			0.591	4

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