Paxillin (PXN) is a multidomain scaffolding protein localized primarily in focal adhesions. It binds with focal adhesion kinase (FAK1, also known as PTK2) and is recruited to the focal adhesions. VEGF induced a quick and marked increase in the recruitment of both paxillin and vinculin to FAK (Abedi & Zachary 1997).
Abedi, H, Zachary, I
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