Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
TRAPPC10 [cytosol]
Stable Identifier
R-HSA-5216159
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Trafficking protein particle complex subunit 10, TPC10_HUMAN, TRAPP2
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
COPII coat binds TRAPPCII and RAB1:GDP (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
CSNK1D phosphorylates SEC23 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
Nucleotide exchange on RAB1 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
COPII coat binds TRAPPCII and RAB1:GDP (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
CSNK1D phosphorylates SEC23 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
Nucleotide exchange on RAB1 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
Rab regulation of trafficking (Homo sapiens)
RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)
TRAPPC complexes exchange GTP for GDP on RAB1 (Homo sapiens)
TRAPPCs [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
TRAPPCIII [cytosol] (Homo sapiens)
TRAPPC10 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P48553 TRAPPC10
Gene Names
TRAPPC10, EHOC1, TMEM1
Chain
chain:1-1259
Reference Genes
BioGPS Gene:7109 TRAPPC10
COSMIC (genes):TRAPPC10 TRAPPC10
CTD Gene:7109 TRAPPC10
dbSNP Gene:7109 TRAPPC10
ENSEMBL:ENSG00000160218 TRAPPC10
HGNC:11868 TRAPPC10
KEGG:hsa:7109 TRAPPC10
Monarch:7109 TRAPPC10
NCBI Gene:7109 TRAPPC10
OMIM:602103 TRAPPC10
UCSC:P48553 TRAPPC10
Reference Transcript
RefSeq:XM_016999834.1 TRAPPC10
RefSeq:NM_003274.4 TRAPPC10
Other Identifiers
11731640_at
11731641_s_at
11731642_a_at
11731643_s_at
11731644_s_at
11750776_a_at
11759619_at
11762840_at
1555446_PM_s_at
1555446_s_at
16923451
208184_PM_s_at
208184_s_at
209412_PM_at
209412_at
38303_at
3923437
3923438
3923440
3923444
3923451
3923452
3923453
3923454
3923455
3923457
3923460
3923461
3923463
3923465
3923467
3923468
3923469
3923470
3923471
3923472
3923473
3923475
3923476
3923477
3923478
3923479
3923480
3923481
3923482
3923483
3923484
3923487
3923488
3923489
3923490
3923491
3923492
3923493
3923494
3923499
3923500
3923501
43642_at
7109
8068974
A_23_P317683
A_33_P3312534
A_33_P3315733
GE53027
GE56249
GO:0005515
GO:0005737
GO:0005794
GO:0005829
GO:0006888
GO:0006891
GO:0006901
GO:0016192
GO:0030008
GO:0034498
GO:0043226
GO:0048193
GO:0099022
GO:1990071
HMNXSV003001754
HMNXSV003010618
HMNXSV003047801
HMNXSV003055222
Hs2Affx.1.303.S1_3p_s_at
ILMN_1717973
ILMN_1778464
ILMN_1779632
PH_hs_0033438
TC21000216.hg
TC21000763.hg
U19252_s_at
U61500_at
g1778032_3p_at
g4507550_3p_a_at
Participates
as a component of
TRAPPCIII [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
Inferred To
Trappc10 [cytosol]
(Mus musculus)
Trappc10 [cytosol]
(Rattus norvegicus)
Ghost homologue of TRAPPC10 [cytosol]
(Danio rerio)
Ghost homologue of TRAPPC10 [cytosol]
(Plasmodium falciparum)
SIDL [cytosol]
(Drosophila melanogaster)
TRAPPC10 [cytosol]
(Bos taurus)
TRAPPC10 [cytosol]
(Canis familiaris)
TRAPPC10 [cytosol]
(Gallus gallus)
TRAPPC10 [cytosol]
(Schizosaccharomyces pombe)
TRAPPC10 [cytosol]
(Sus scrofa)
TRS130 [cytosol]
(Saccharomyces cerevisiae)
trapcc10-1 [cytosol]
(Dictyostelium discoideum)
trappc10 [cytosol]
(Xenopus tropicalis)
trpp-10 [cytosol]
(Caenorhabditis elegans)
Cross References
ENSEMBL
ENST00000291574
,
ENST00000380221
,
ENSP00000291574
,
ENSP00000369570
OpenTargets
ENSG00000160218
HPA
ENSG00000160218-TRAPPC10
PRO
P48553
Pharos - Targets
P48553
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96QF0 RAB3IP
1
RAB3IP [cytosol]
(R-HSA-5617610)
0.775
8
UniProt:Q9BZR8 BCL2L14
1
BCL2L14 [cytosol]
(R-HSA-6791317)
0.643
4
UniProt:Q9P2M4 TBC1D14
1
TBC1D14 [recycling endosome]
(R-HSA-8854764)
0.527
2
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text