Reactome | SLC25A18 [mitochondrial inner membrane]

SLC25A18 [mitochondrial inner membrane]

Stable Identifier

R-HSA-5216134

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Mitochondrial glutamate carrier 2, GHC2_HUMAN

Locations in the PathwayBrowser

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Metabolism (Homo sapiens)

- Aerobic respiration and respiratory electron transport (Homo sapiens)
  - Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Homo sapiens)
    - Respiratory electron transport (Homo sapiens)
      - Malate-aspartate shuttle (Homo sapiens)
        
        SLC25A18,22 import L-Glu, H+ (Homo sapiens)
        
        SLC25A18,A22 [mitochondrial inner membrane] (Homo sapiens)
        
        SLC25A18 [mitochondrial inner membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9H1K4 SLC25A18

Gene Names

SLC25A18, GC2

Chain

chain:1-315

Reference Genes

BioGPS Gene:83733 SLC25A18

COSMIC (genes):SLC25A18 SLC25A18

CTD Gene:83733 SLC25A18

dbSNP Gene:83733 SLC25A18

ENSEMBL:ENSG00000182902 SLC25A18

ENSEMBL_homo_sapiens_GENE:ENSG00000182902.14 SLC25A18

HGNC:10988 SLC25A18

KEGG Gene (Homo sapiens):83733 SLC25A18

Monarch:83733 SLC25A18

NCBI Gene:83733 SLC25A18

OMIM:609303 SLC25A18

UCSC:Q9H1K4 SLC25A18

Reference Transcript

Other Identifiers

11731029_a_at

16926875

223605_PM_at

223605_at

3936225

3936228

3936229

3936232

3936233

3936236

3936237

3936240

3936244

3936246

3936248

3936249

3936251

3936252

3936253

54979_at

8071107

83733

A_24_P74508

GE80826

GO:0005215

GO:0005280

GO:0005313

GO:0005515

GO:0005739

GO:0005743

GO:0006091

GO:0006811

GO:0015183

GO:0015293

GO:0015810

GO:0015813

GO:0016020

GO:0043226

GO:0043490

GO:0055085

GO:0070778

GO:1902600

HMNXSV003049977

HMNXSV003056905

ILMN_1754864

PH_hs_0014577

TC22000024.hg

g11999276_3p_at

Participates

as a member of

SLC25A18,A22 [mitochondrial inner membrane] (Homo sapiens)

Inferred To

slc-25a18.1 [mitochondrial inner membrane] (Caenorhabditis elegans)

slc25a18 [mitochondrial inner membrane] (Xenopus tropicalis)

SLC25A18 [mitochondrial inner membrane] (Canis familiaris)

SLC25A18 [mitochondrial inner membrane] (Danio rerio)

SLC25A18 [mitochondrial inner membrane] (Dictyostelium discoideum)

GC1 [mitochondrial inner membrane] (Drosophila melanogaster)

AGC1 [mitochondrial inner membrane] (Saccharomyces cerevisiae)

Slc25a18 [mitochondrial inner membrane] (Mus musculus)

Slc25a18 [mitochondrial inner membrane] (Rattus norvegicus)

Cross References

RefSeq

XP_011544455.1, XP_011544454.1, XP_011544453.1, XP_016884457.1, NP_001290413.1, NP_113669.1, XP_011544456.1

Guide to Pharmacology - Targets

1056

OpenTargets

ENSG00000182902

GeneCards

Q9H1K4

HPA

ENSG00000182902-SLC25A18

Ensembl

ENSP00000382710, ENST00000399813, ENST00000327451, ENSG00000182902, ENSP00000329033

PRO

Q9H1K4

Pharos - Targets

Q9H1K4

HMDB Protein

HMDBP03104