Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
SLC25A27 [mitochondrial inner membrane]
Stable Identifier
R-HSA-5216059
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
UCP4, Mitochondrial uncoupling protein 4
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Mitochondrial Uncoupling (Homo sapiens)
The fatty acid cycling model (Homo sapiens)
FA anion diffuses laterally to UCP (Homo sapiens)
FA anion:UCP dimer "head-in" complex [mitochondrial inner membrane] (Homo sapiens)
UCP dimer [mitochondrial inner membrane] (Homo sapiens)
UCP [mitochondrial inner membrane] (Homo sapiens)
SLC25A27 [mitochondrial inner membrane] (Homo sapiens)
UCP dimer [mitochondrial inner membrane] (Homo sapiens)
UCP [mitochondrial inner membrane] (Homo sapiens)
SLC25A27 [mitochondrial inner membrane] (Homo sapiens)
FA anion flip-flops to the opposite surface (Homo sapiens)
FA anion:UCP dimer "head-out" complex [mitochondrial inner membrane] (Homo sapiens)
UCP dimer [mitochondrial inner membrane] (Homo sapiens)
UCP [mitochondrial inner membrane] (Homo sapiens)
SLC25A27 [mitochondrial inner membrane] (Homo sapiens)
FA anion:UCP dimer "head-in" complex [mitochondrial inner membrane] (Homo sapiens)
UCP dimer [mitochondrial inner membrane] (Homo sapiens)
UCP [mitochondrial inner membrane] (Homo sapiens)
SLC25A27 [mitochondrial inner membrane] (Homo sapiens)
UCP dimer [mitochondrial inner membrane] (Homo sapiens)
UCP [mitochondrial inner membrane] (Homo sapiens)
SLC25A27 [mitochondrial inner membrane] (Homo sapiens)
The FA anion diffuses away laterally from UCP (Homo sapiens)
FA anion:UCP dimer "head-out" complex [mitochondrial inner membrane] (Homo sapiens)
UCP dimer [mitochondrial inner membrane] (Homo sapiens)
UCP [mitochondrial inner membrane] (Homo sapiens)
SLC25A27 [mitochondrial inner membrane] (Homo sapiens)
UCP dimer [mitochondrial inner membrane] (Homo sapiens)
UCP [mitochondrial inner membrane] (Homo sapiens)
SLC25A27 [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O95847 SLC25A27
Gene Names
SLC25A27, UCP4, UNQ772/PRO1566
Chain
chain:1-323
Reference Genes
BioGPS Gene:9481 SLC25A27
COSMIC (genes):SLC25A27 SLC25A27
CTD Gene:9481 SLC25A27
dbSNP Gene:9481 SLC25A27
ENSEMBL:ENSG00000153291 SLC25A27
ENSEMBL_homo_sapiens_GENE:ENSG00000153291.16 SLC25A27
HGNC:21065 SLC25A27
KEGG Gene (Homo sapiens):9481 SLC25A27
Monarch:9481 SLC25A27
NCBI Gene:9481 SLC25A27
OMIM:613725 SLC25A27
UCSC:O95847 SLC25A27
Reference Transcript
RefSeq:NM_004277.4 SLC25A27
RefSeq:NM_001204052.1 SLC25A27
RefSeq:NM_001204051.1 SLC25A27
Other Identifiers
11727864_a_at
11727865_a_at
11727866_x_at
11745023_x_at
11745380_a_at
11750183_a_at
1552774_PM_a_at
1552774_a_at
1554161_PM_at
1554161_at
17009333
230624_PM_at
230624_at
231787_PM_at
231787_at
2909170
2909171
2909172
2909173
2909177
2909181
2909183
2909184
2909187
2909189
2909192
2909196
2909197
2909198
2909199
2909200
2909201
2909202
2909203
2909204
2909205
73839_at
77110_at
8120067
9481
A_23_P81721
A_24_P246841
A_33_P3412468
GE54817
GO:0005215
GO:0005739
GO:0005743
GO:0008284
GO:0009409
GO:0010917
GO:0012501
GO:0015078
GO:0015108
GO:0016020
GO:0022857
GO:0031966
GO:0035356
GO:0042803
GO:0043025
GO:0043066
GO:0043226
GO:0043524
GO:0045177
GO:0046324
GO:0048839
GO:0048856
GO:0051562
GO:0055065
GO:0055085
GO:1902476
GO:1902600
HMNXSV003052119
Hs.145008.0.A1_3p_at
Hs.40510.1.S2_3p_at
Hs2.40510.1.S1_3p_s_at
Hs2.40510.2.S1_3p_at
ILMN_1698726
PH_hs_0031176
TC06000628.hg
Participates
as a member of
UCP [mitochondrial inner membrane] (Homo sapiens)
Inferred To
Ucp4A [mitochondrial inner membrane]
(Drosophila melanogaster)
ucp-4 [mitochondrial inner membrane]
(Caenorhabditis elegans)
Slc25a27 [mitochondrial inner membrane]
(Mus musculus)
Slc25a27 [mitochondrial inner membrane]
(Rattus norvegicus)
slc25a27 [mitochondrial inner membrane]
(Danio rerio)
slc25a27 [mitochondrial inner membrane]
(Xenopus tropicalis)
SLC25A27 [mitochondrial inner membrane]
(Bos taurus)
SLC25A27 [mitochondrial inner membrane]
(Canis familiaris)
SLC25A27 [mitochondrial inner membrane]
(Sus scrofa)
Cross References
RefSeq
NP_004268.3
,
NP_001190981.1
,
NP_001190980.1
Guide to Pharmacology - Targets
1069
OpenTargets
ENSG00000153291
HPA
ENSG00000153291-SLC25A27
GeneCards
O95847
Ensembl
ENSP00000360398
,
ENST00000371347
,
ENST00000411689
,
ENSP00000412024
,
ENSG00000153291
PRO
O95847
Pharos - Targets
O95847
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text