Reactome | ATP5MC2 [mitochondrial inner membrane]

ATP5MC2 [mitochondrial inner membrane]

Stable Identifier

R-HSA-5215956

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

ATP synthase subunit f, ATP5G2, AT5G2_HUMAN

Locations in the PathwayBrowser

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Metabolism (Homo sapiens)

- Aerobic respiration and respiratory electron transport (Homo sapiens)
  - Formation of ATP by chemiosmotic coupling (Homo sapiens)
    - ADP and Pi bind to ATPase (Homo sapiens)
      - ATPase:ADP:Pi [mitochondrial inner membrane] (Homo sapiens)
        
        F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        ATP synthase subunit c [mitochondrial inner membrane] (Homo sapiens)
        
        ATP5MC2 [mitochondrial inner membrane] (Homo sapiens)
      - F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        ATP synthase subunit c [mitochondrial inner membrane] (Homo sapiens)
        
        ATP5MC2 [mitochondrial inner membrane] (Homo sapiens)
    - ATPase synthesizes ATP (Homo sapiens)
      - ATPase:ADP:Pi [mitochondrial inner membrane] (Homo sapiens)
        
        F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        ATP synthase subunit c [mitochondrial inner membrane] (Homo sapiens)
        
        ATP5MC2 [mitochondrial inner membrane] (Homo sapiens)
      - ATPase:ATP [mitochondrial inner membrane] (Homo sapiens)
        
        F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        ATP synthase subunit c [mitochondrial inner membrane] (Homo sapiens)
        
        ATP5MC2 [mitochondrial inner membrane] (Homo sapiens)
      - F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        ATP synthase subunit c [mitochondrial inner membrane] (Homo sapiens)
        
        ATP5MC2 [mitochondrial inner membrane] (Homo sapiens)
    - Enzyme-bound ATP is released (Homo sapiens)
      - ATPase:ATP [mitochondrial inner membrane] (Homo sapiens)
        
        F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        ATP synthase subunit c [mitochondrial inner membrane] (Homo sapiens)
        
        ATP5MC2 [mitochondrial inner membrane] (Homo sapiens)
      - F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        ATP synthase subunit c [mitochondrial inner membrane] (Homo sapiens)
        
        ATP5MC2 [mitochondrial inner membrane] (Homo sapiens)

Organelle biogenesis and maintenance (Homo sapiens)

- Mitochondrial biogenesis (Homo sapiens)
  - Cristae formation (Homo sapiens)
    - F1Fo ATP synthase dimerizes (Homo sapiens)
      - F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        ATP synthase subunit c [mitochondrial inner membrane] (Homo sapiens)
        
        ATP5MC2 [mitochondrial inner membrane] (Homo sapiens)
      - F1Fo ATP synthase dimer [mitochondrial inner membrane] (Homo sapiens)
        
        F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        ATP synthase subunit c [mitochondrial inner membrane] (Homo sapiens)
        
        ATP5MC2 [mitochondrial inner membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q06055 ATP5MC2

Gene Names

ATP5MC2, ATP5G2, PSEC0033

Chain

transit peptide:1-66, chain:67-141

Reference Genes

BioGPS Gene:517 ATP5MC2

COSMIC (genes):ATP5MC2 ATP5MC2

CTD Gene:517 ATP5MC2

dbSNP Gene:517 ATP5MC2

ENSEMBL:ENSG00000135390 ATP5G2

HGNC:842 ATP5MC2

KEGG:hsa:517 ATP5MC2

Monarch:517 ATP5MC2

NCBI Gene:517 ATP5MC2

OMIM:603193 ATP5MC2

UCSC:Q06055 ATP5MC2

Reference Transcript

Other Identifiers

11715848_a_at

16765389

207552_PM_at

207552_at

208764_3p_s_at

208764_PM_s_at

208764_s_at

3456311

3456318

3456319

3456320

3456321

3456322

3456323

3456326

3456327

3456329

3456330

3456331

3456333

3456334

3456336

3456337

3456338

3456339

3456340

3456341

3456342

3456343

3456344

3538148

38777_at

517

7963713

A_21_P0011094

A_23_P87616

A_24_P315326

GE572189

GE59964

GE61224

GO:0005215

GO:0005515

GO:0005739

GO:0005743

GO:0008289

GO:0015078

GO:0015986

GO:0016020

GO:0031966

GO:0033177

GO:0043226

GO:0045263

GO:0055085

GO:0055086

GO:1901135

GO:1902600

HMNXSV003010992

Hs.247790.0.S1_3p_s_at

ILMN_1660577

ILMN_1669102

ILMN_1807798

PH_hs_0031395

TC12001553.hg

TC12002893.hg

X69908_rna1_at

g285909_3p_a_at

g285909_3p_x_at

g6671590_3p_a_at

g6671590_3p_at

p27140

Participates

as a member of

ATP synthase subunit c [mitochondrial inner membrane] (Homo sapiens)

Inferred To

atp5mc3b [mitochondrial inner membrane] (Danio rerio)

ATP5MC2 [mitochondrial inner membrane] (Caenorhabditis elegans)

ATP5MC2 [mitochondrial inner membrane] (Canis familiaris)

ATP5MC2 [mitochondrial inner membrane] (Gallus gallus)

ATP5MC2 [mitochondrial inner membrane] (Sus scrofa)

ATPsynC [mitochondrial inner membrane] (Drosophila melanogaster)

Atp5mc2 [mitochondrial inner membrane] (Mus musculus)

Atp5mc1 [mitochondrial inner membrane] (Rattus norvegicus)

Cross References

ENSEMBL

ENSP00000377878, ENSP00000448801, ENSP00000340315, ENSP00000447317, ENST00000394349, ENSP00000499883, ENST00000673498, ENST00000338662, ENST00000549164, ENST00000552242

OpenTargets

ENSG00000135390

HPA

ENSG00000135390-ATP5MC2

PRO

Q06055

Pharos - Targets

Q06055