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SV2A [plasma membrane]
Stable Identifier
R-HSA-5215949
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Synaptic vesicle glycoprotein 2A, SV2A_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Uptake and actions of bacterial toxins (Homo sapiens)
Neurotoxicity of clostridium toxins (Homo sapiens)
Toxicity of botulinum toxin type A (botA) (Homo sapiens)
botA HC:LC binds SV2A, B, or C and GT1b on the target cell surface (Homo sapiens)
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2A [plasma membrane] (Homo sapiens)
botA HC:LC dimer:SV2:GT1b [plasma membrane] (Homo sapiens)
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2A [plasma membrane] (Homo sapiens)
botA:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)
botA HC:LC dimer:SV2:GT1b [plasma membrane] (Homo sapiens)
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2A [plasma membrane] (Homo sapiens)
Toxicity of botulinum toxin type D (botD) (Homo sapiens)
botD HC:LC binds SV2A or B or C and GD2 on the target cell surface (Homo sapiens)
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2A [plasma membrane] (Homo sapiens)
botD:SV2:GD2 [plasma membrane] (Homo sapiens)
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2A [plasma membrane] (Homo sapiens)
botD:SV2:GD2 internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)
botD:SV2:GD2 [plasma membrane] (Homo sapiens)
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2A [plasma membrane] (Homo sapiens)
Toxicity of botulinum toxin type E (botE) (Homo sapiens)
botE HC:LC binds SV2A or B and GT1b on the target cell surface (Homo sapiens)
SV2A,B [plasma membrane] (Homo sapiens)
SV2A [plasma membrane] (Homo sapiens)
botE:SV2:GT1b [plasma membrane] (Homo sapiens)
SV2A,B [plasma membrane] (Homo sapiens)
SV2A [plasma membrane] (Homo sapiens)
botE:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)
botE:SV2:GT1b [plasma membrane] (Homo sapiens)
SV2A,B [plasma membrane] (Homo sapiens)
SV2A [plasma membrane] (Homo sapiens)
Toxicity of botulinum toxin type F (botF) (Homo sapiens)
botF HC:LC binds SV2A or B or C and GT1b on the target cell surface (Homo sapiens)
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2A [plasma membrane] (Homo sapiens)
botF:SV2:GT1b [plasma membrane] (Homo sapiens)
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2A [plasma membrane] (Homo sapiens)
botF:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)
botF:SV2:GT1b [plasma membrane] (Homo sapiens)
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2A [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7L0J3 SV2A
Gene Names
SV2A, KIAA0736, PSEC0174
Chain
chain:1-742
Reference Genes
BioGPS Gene:9900 SV2A
COSMIC (genes):SV2A SV2A
CTD Gene:9900 SV2A
dbSNP Gene:9900 SV2A
ENSEMBL:ENSG00000159164 SV2A
HGNC:20566 SV2A
Monarch:9900 SV2A
NCBI Gene:9900 SV2A
OMIM:185860 SV2A
UCSC:Q7L0J3 SV2A
Reference Transcript
RefSeq:NM_001328675.1 SV2A
RefSeq:NM_001328674.1 SV2A
RefSeq:NM_001278719.1 SV2A
RefSeq:NM_014849.4 SV2A
Other Identifiers
11719653_at
11719654_a_at
11719655_at
16692639
203069_PM_at
203069_at
2434140
2434141
2434142
2434143
2434145
2434147
2434148
2434149
2434150
2434151
2434152
2434154
2434155
2434156
2434157
2434158
38032_at
7919645
9900
A_23_P23728
A_24_P131236
GE53449
GO:0005215
GO:0005783
GO:0005886
GO:0005911
GO:0006836
GO:0006874
GO:0007268
GO:0008021
GO:0014052
GO:0016020
GO:0016082
GO:0019901
GO:0022857
GO:0023052
GO:0030425
GO:0030672
GO:0031410
GO:0031594
GO:0042995
GO:0043005
GO:0043025
GO:0043226
GO:0045202
GO:0048786
GO:0055085
GO:0065003
GO:0098793
GO:0098978
GO:0098982
HMNXSV003056341
ILMN_1702009
PH_hs_0030955
TC01003195.hg
g7662271_3p_at
Participates
as a member of
SV2A,B,C [plasma membrane] (Homo sapiens)
SV2A,B [plasma membrane] (Homo sapiens)
Other forms of this molecule
SV2A [synaptic vesicle membrane]
Cross References
Guide to Pharmacology - Targets
2634
ENSEMBL
ENST00000369145
,
ENST00000369146
,
ENSP00000358141
,
ENSP00000358142
OpenTargets
ENSG00000159164
HPA
ENSG00000159164-SV2A
PRO
Q7L0J3
Pharos - Targets
Q7L0J3
GlyGen
Q7L0J3
HMDB Protein
HMDBP08020
PDB
8JS8
,
8UOA
,
8JLG
,
8JS9
,
8JLF
,
8YF1
,
8JLI
,
8UO9
,
8JLH
,
8K77
,
8YF0
,
8JLC
,
8JLE
,
4V11
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