Reactome | SLC38A9 [lysosomal membrane]

SLC38A9 [lysosomal membrane]

Stable Identifier

R-HSA-5215938

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

lysosomal membrane

Synonyms

Putative sodium-coupled neutral amino acid transporter 9, S38A9_HUMAN

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Locations in the PathwayBrowser for interactor UniProt:Q5VZM2 RRAGB

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External Reference Information

External Reference

UniProt:Q8NBW4 SLC38A9

Gene Names

SLC38A9, URLC11

Chain

chain:1-561

Reference Genes

BioGPS Gene:153129 SLC38A9

COSMIC (genes):SLC38A9 SLC38A9

CTD Gene:153129 SLC38A9

dbSNP Gene:153129 SLC38A9

ENSEMBL:ENSG00000177058 SLC38A9

HGNC:26907 SLC38A9

KEGG:hsa:153129 SLC38A9

Monarch:153129 SLC38A9

NCBI Gene:153129 SLC38A9

OMIM:616203 SLC38A9

UCSC:Q8NBW4 SLC38A9

Reference Transcript

Other Identifiers

11730324_s_at

11755940_a_at

11756786_x_at

153129

235241_PM_at

235241_at

242330_PM_at

242330_at

243709_PM_at

243709_at

2591162

2744476

2857309

2857310

2857311

2857312

2857313

2857315

2857318

2857319

2857320

2857321

2857322

2857323

2857326

2857327

2857328

2857329

2857330

2857331

2857332

2857333

2857334

2857335

2857336

2857338

2857339

2857340

2857341

2857342

2857343

2857344

2857345

2857346

2857353

2857354

2857355

2857356

2857357

2857358

2857359

2857360

2857361

2857362

2857363

2857364

2857365

2857374

53691_at

74325_at

76235_at

8112121

A_32_P126311

GE525488

GO:0003333

GO:0005085

GO:0005215

GO:0005515

GO:0005764

GO:0005765

GO:0005768

GO:0005770

GO:0005773

GO:0006865

GO:0006867

GO:0006868

GO:0008289

GO:0015171

GO:0015179

GO:0015182

GO:0015186

GO:0015190

GO:0015485

GO:0015803

GO:0016020

GO:0031410

GO:0031902

GO:0032008

GO:0032935

GO:0034618

GO:0043226

GO:0046872

GO:0055085

GO:0061459

GO:0071230

GO:0071986

GO:0098772

GO:0140299

GO:1903826

GO:1904263

GO:1990877

HMNXSV003039314

Hs.120506.0.A1_3p_at

Hs.55560.0.A1_3p_at

ILMN_1773643

PH_hs_0018453

Participates

as a component of

as an input of

SLC38A9 binds Ragulator:Rag dimers (Homo sapiens)

Inferred To

Ghost homologue of SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)

Ghost homologue of SLC38A9 [lysosomal membrane] (Drosophila melanogaster)

Ghost homologue of SLC38A9 [lysosomal membrane] (Schizosaccharomyces pombe)

SLC38A9 [lysosomal membrane] (Bos taurus)

SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)

SLC38A9 [lysosomal membrane] (Canis familiaris)

SLC38A9 [lysosomal membrane] (Danio rerio)

SLC38A9 [lysosomal membrane] (Gallus gallus)

SLC38A9 [lysosomal membrane] (Mus musculus)

SLC38A9 [lysosomal membrane] (Rattus norvegicus)

SLC38A9 [lysosomal membrane] (Sus scrofa)

SLC38A9 [lysosomal membrane] (Xenopus tropicalis)

Cross References

RefSeq

XP_006714602.1, NP_775785.2, NP_001245216.1, NP_001245215.1, XP_011541475.1, XP_011541476.1, XP_006714601.1, XP_006714600.1

Guide to Pharmacology - Targets

1177

OpenTargets

ENSG00000177058

ENSEMBL

ENSP00000316596, ENSP00000420934, ENST00000515629, ENST00000512595, ENSP00000427335, ENSP00000380074, ENSG00000177058, ENST00000396865, ENST00000318672

HPA

ENSG00000177058-SLC38A9

GeneCards

SLC38A9

PRO

Q8NBW4

Pharos - Targets

Q8NBW4

GlyGen

Q8NBW4

PDB

6WJ3, 8DHB, 6WJ2

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q7L523 RRAGA	2	RRAGA [cytosol] (R-HSA-5653577) K63polyUb-K142,K220,K230,K244-RRAGA [cytosol] (R-HSA-8938830)	0.829	17
UniProt:Q6IAA8 LAMTOR1	5	LAMTOR1 [lysosomal membrane] (R-HSA-5653582) LAMTOR1 [specific granule membrane] (R-HSA-6799631) LAMTOR1 [plasma membrane] (R-HSA-6806270) LAMTOR1 [azurophil granule membrane] (R-HSA-6799633) LAMTOR1 [ficolin-1-rich granule membrane] (R-HSA-6801003)	0.767	15
UniProt:Q0VGL1 LAMTOR4	1	LAMTOR4 [lysosomal membrane] (R-HSA-5655432)	0.723	6
UniProt:O43504 LAMTOR5	1	LAMTOR5 [lysosomal membrane] (R-HSA-5655441)	0.723	6
UniProt:Q9Y2Q5 LAMTOR2	5	LAMTOR2 [lysosomal membrane] (R-HSA-5653583) LAMTOR2 [endosome membrane] (R-HSA-5693293) LAMTOR2 [tertiary granule membrane] (R-HSA-6800165) LAMTOR2 [plasma membrane] (R-HSA-6806286) LAMTOR2 [specific granule membrane] (R-HSA-6800168)	0.669	5
UniProt:Q9HB90 RRAGC	1	RRAGC [cytosol] (R-HSA-5653949)	0.662	9
UniProt:Q9UHA4 LAMTOR3	5	LAMTOR3 [lysosomal membrane] (R-HSA-5653581) LAMTOR3 [endosome membrane] (R-HSA-5693294) LAMTOR3 [tertiary granule membrane] (R-HSA-6800189) LAMTOR3 [plasma membrane] (R-HSA-6806307) LAMTOR3 [specific granule membrane] (R-HSA-6800178)	0.623	7
UniProt:Q5VZM2 RRAGB	1	RRAGB [cytosol] (R-HSA-5653579)	0.564	2
UniProt:O14894 T4S5			0.463	4

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