lef (Anthrax LF, lethal factor) a zinc metalloprotease (Klimpel et al, 1994) in the target cell cytosol, cleaves MAP2K6 (MEK6, mitogen activated protein kinase kinase 6), isoform 1 (Vitale et al. 2000).
Mock, M, Napolitani, G, Montecucco, C, Bernardi, L, Vitale, G
Klimpel, KR, Leppla, SH, Arora, N
metallopeptidase activity of lef [cytosol]
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