MAP2K2(1-10) [cytosol]

Stable Identifier
R-HSA-5211334
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
MAP2K2 small LF fragment
Icon
MAP2K2(1-10) [cytosol] icon
MAP2K2(1-10) [cytosol] icon
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
9703991 Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages

Vitale, G, Pellizzari, R, Recchi, C, Napolitani, G, Mock, M, Montecucco, C

Biochem. Biophys. Res. Commun. 1998
9563949 Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

Duesbery, NS, Webb, CP, Leppla, SH, Gordon, VM, Klimpel, KR, Copeland, TD, Ahn, NG, Oskarsson, MK, Fukasawa, K, Paull, KD, Vande Woude, GF

Science 1998
External Reference Information
External Reference
UniProt:P36507 MAP2K2
Gene Names
MAP2K2, MEK2, MKK2, PRKMK2
Chain
chain:1-400
Reference Genes
BioGPS Gene:5605 MAP2K2
COSMIC (genes):MAP2K2 MAP2K2
CTD Gene:5605 MAP2K2
dbSNP Gene:5605 MAP2K2
ENSEMBL:ENSG00000126934 MAP2K2
ENSEMBL_homo_sapiens_GENE:ENSG00000126934 MAP2K2
HGNC:6842 MAP2K2
KEGG Gene (Homo sapiens):5605 MAP2K2
Monarch:5605 MAP2K2
NCBI Gene:5605 MAP2K2
OMIM:601263 MAP2K2
UCSC:P36507 MAP2K2
Reference Transcript
Other Identifiers
0003710047
1131_at
11716318_x_at
1S9I
202424_at
213490_s_at
3023305
3023308
3023309
3023310
3835
3846639
3846640
3846643
3846645
3846646
3846650
3846652
3846653
3846654
3846659
3846660
3846663
3846664
3846665
3846666
4H3Q
51993
5605
8032761
A_23_P208835
AAH00471
AAH18645
BC000471
BC018645
CAB003835
CCDS12120
ENSG00000126934
ENSP00000262948
ENST00000262948
EntrezGene:5605
g13489053_3p_at
g13489053_3p_x_at
G5E9C7
GE57609
GO:0000165
GO:0000166
GO:0000187
GO:0003674
GO:0004672
GO:0004674
GO:0004708
GO:0004712
GO:0004713
GO:0005515
GO:0005524
GO:0005575
GO:0005576
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005739
GO:0005768
GO:0005769
GO:0005770
GO:0005777
GO:0005778
GO:0005783
GO:0005794
GO:0005829
GO:0005856
GO:0005874
GO:0005886
GO:0005911
GO:0005925
GO:0006412
GO:0006464
GO:0006468
GO:0006810
GO:0006950
GO:0007165
GO:0008150
GO:0009058
GO:0009898
GO:0010629
GO:0016020
GO:0016192
GO:0016301
GO:0016310
GO:0016740
GO:0018108
GO:0023014
GO:0030165
GO:0030234
GO:0031098
GO:0031410
GO:0032147
GO:0032872
GO:0034641
GO:0036289
GO:0043167
GO:0043226
GO:0043539
GO:0045893
GO:0046872
GO:0048471
GO:0070371
GO:0071902
GO:0090170
GO:0097110
GO:1903800
GO:2000641
HGNC:6842
HPA051993
Hs.72241.1.S1_3p_a_at
ILMN_1657968
ILMN_1752423
IPR000719
IPR008271
IPR011009
IPR017441
L11285
L11285_at
LRG_750
MAP2K2
MAP2K2-201
MIM:601263
MIM:615280
NM_030662
NP_109587
PF00069
PH_hs_0029886
SM00220
TC19001058.hg
uc002lzk.4
UPI000012F489
XM_006722799
XM_017026989
XP_006722862
XP_016882478
Participant Of
output
Other forms of this molecule
p-S,T-MAP2K2 [cytosol]
p-S222,S226-MAP2K2 [cytosol]
MAP2K2 [cytosol]
MAP2K2(11-400) [cytosol]
Disease
Name Identifier Synonyms
anthrax disease 7427
Cross References
RefSeq
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
PDB
GeneCards
DOCK Blaster
BRENDA (Homo sapiens)
ZINC - Predictions - Purchasable
Orphanet
HMDB Protein
Interactors (11)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P10398 ARAF  4 0.791 6
 UniProt:P15056 BRAF  32 0.669 6
 UniProt:P04049 RAF1  10 0.667 3
 UniProt:O95273 CCDB1      0.556 3
 UniProt:Q92905 COPS5  2 0.553 2
 UniProt:Q8IVT5 KSR1  5 0.547 6
 UniProt:Q12959 DLG1  2 0.543 10
 UniProt:Q61097  5 0.508 2
 UniProt:P61978-2 HNRNPK      0.488 2
 UniProt:P00540 MOS      0.488 2
 UniProt:Q96II5 Q96II5      0.488 2