SIRT1 deacetylates TAF1B in SL1 complex

Stable Identifier
R-HSA-5211239
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

As inferred from mouse, SIRT1, an NAD+ dependent deacetylase, deacetylates the TAF1B (TAF(1)68) subunit of the SL1 complex. Deacetylation of TAF1B inhibits transcription of rRNA genes.

Participants
Participates
Catalyst Activity

NAD-dependent protein deacetylase activity of SIRT1 [nucleoplasm]

Inferred From
Authored
Reviewed
Created
Cite Us!