ANTXR2 (Anthrax Receptor 2)-bound pagA(197-794) (protective antigen, large fragment) forms oligomers in the target cell plasma membrane. Initial studies indicated that these were heptamers (Lacy et al. 2004; Santelli et al. 2004; Wigelsworth et al. 2004; Young and Collier 2007). More recent work has established that octamers also form and suggests that the octaneric structure is more stable under physiological conditions (Kintzer et al. 2009, 2010). Formation of the latter structure is thus annotated here.
Young, JA, Collier, RJ
Wigelsworth, DJ, Melnyk, RA, Lacy, DB, Collier, RJ, Harrison, SC
Abdul-Gader, A, Krantz, BA, Williams, ER, Miles, AJ, Sterling, HJ, Tang, II, Kintzer, AF, Wallace, BA
Wigelsworth, DJ, Krantz, BA, Lacy, DB, Collier, RJ, Juris, SJ, Christensen, KA
Santelli, E, Leppla, SH, Liddington, RC, Bankston, LA
Krantz, BA, Williams, ER, Sterling, HJ, Tang, II, Thoren, KL, Kintzer, AF, Berger, JM, Feld, GK, Zhang, TT, Dong, KC
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